The School of Biotechnology and Biomolecular Sciences at UNSW

The University of New South Wales

A leading research and teaching school with expertise in biotechnology, molecular biology, genetics, environmental microbiology, medical microbiology, immunology, biochemistry, protein chemistry and other areas of biological science.

Active Research Projects

Publications

Gunawan C., Breuer, M., Hauer, B., Rogers, P.L., Rosche, B. (2008)
Improved (R)-phenylacetylcarbinol production with Candida utilis pyruvate decarboxylase at decreased organic to aqueous phase volume ratios.
Biotech Letters 30: 281-286
Li, X.Z., Hauer, B., Rosche, B. (2007)
Single-species microbial biofilm screening for industrial applications.
Applied Microbiol Biotech, 76: 1255-1262
Muller, A., Hauer, B. and Rosche, B. (2007)
Asymmetric alkene reduction by yeast old yellow enzymes and by a novel Zymomonas mobilis reductase.
Biotech Bioeng 98: 22-29
Muller, A., Sturmer, R., Hauer, B. and Rosche, B. (2007)
Stereospecific alkyne reduction:  novel activity of Old Yellow Enzymes.
Angew Chem Int Ed 46: 3316-3318
Gunawan, C., Satianegara, G., Chen, A., Breuer, M., Hauer, B., Rogers, P., Rosche, B. (2007)
Yeast pyruvate decarboxylases:  Variation in biocatalytic characteristics for (R)-phenylacetylcarbinol production.
FEMS Yeast Research 7: 33-39
Li, XZ., Webb, J.S., Kjelleberg, S., Rosche, B. (2006)
Enhanced benzaldehyde tolerance in Zymomonas mobilis biofilms and the potential of biofilm applications in fine chemical production.
Appl Environ Microbiol 72: 1639-1644
Muller, A., Hauer, B., Rosche, B. (2006)
Enzymatic reduction of the α,β-unsaturated carbon bond in citral.
J Mol Cat B: Enzymatic 38: 126-130
Li, D., Teoh, W.Y., Selomulya, C., Woodward, R.C., Amal, R. and Rosche, B. (2006)
Flame-sprayed superparamagnetic bare and silica-coated maghemite nanoparticles: synthesis, characterization and protein adsorption-desorption
Chemistry of Materials.  18: 6403-6413
Satianegara, G., Rogers, P. and Rosche, B. (2006)
Comparative studies on enzyme preparations and role of cell components for (R)-phenylacetylcarbinol production in a two-phase biotransformation
Biotech Bioeng.  94: 1189-1195
Satianegara, G., Breuer, M., Hauer, B., Rogers, P. and Rosche, B. (2006)
Enzymatic (R)-phenylacetylcarbinol production in a benzaldehyde emulsion system with Candida utilis cells
Appl Microb Biotech.  70: 170-175
Leksawasdi, N., Rosche, B. and Rogers, P. (2006)
Enzymatic processes for fine chemicals and pharmaceuticals: Kinetic simulation for optimal R-phenylacetylcarbinol production
In: Studies in Surface Science and Catalysis, New Developments and Application in Chemical Reaction Engineering, Vol. 159 (Hyun-Ku Rhee, In-Sik Nam and Jong Moon Park eds.) Elsevier Science: New York, ISBN 0-444-51733-2, pp 27-34.
Leksawasdi, N., Rogers, P. amd Rosche, B. (2005)
Improved enzymatic two-phase biotransformation for (R)-phenylacetylcarbinol: Effect of dipropylene glycol and modes of pH control.
Biocat Biotrans. 23: 445 - 451
Chen, A.K., Breuer, M., Hauer, B., Rogers, P. and Rosche, B. (2005)
pH shift enhancement of Candida utilis pyruvate decarboxylase production
Biotech Bioeng.  92: 183-188
Sandford, V., Breuer, M., Hauer, B., Rogers, P. and Rosche, B. (2005)
(R)-phenylacetylcarbinol production in aqueous/organic two-phase systems using partially purified pyruvate decarboxylase from Candida utilis
Biotech Bioeng.  91: 190-198
Rosche B, Breuer M, Hauer B, Rogers P (2005)
Cells of Candida utilis for in vitro (R)-phenylacetylcarbinol production in an aqueous/octanol two-phase reactor
Biotech Letters 27: 575-581.
Leksawasdi, N., Rosche, B. and Rogers, P. (2005)
Mathematical model for kinetics of enzymatic conversion of benzaldehyde and pyruvate to (R)-phenylacetylcarbinol.
Biochem Eng J.  23: 211-220
Rosche, B., Breuer, M., Hauer, B. & Rogers, P. (2005)
Role of pyruvate in enhancing pyruvate decarboxylase stability towards benzaldehyde
J Biotech.  115: 91-99.
Leksawasdi, N., Breuer, M., Hauer, B., Rosche, B. and Rogers, P. (2004)
Kinetic analysis and modelling of enzymatic (R)-phenylacetylcarbinol batch biotransformation process
J Biotech. 111: 179–189.
Rosche, B., Breuer, M., Hauer, B. and Rogers, P. (2004)
Biphasic aqueous/organic biotransformation of acetaldehyde and benzaldehyde by Zymomonas mobilis pyruvate decarboxylase
Biotech Bioeng 86: 788-794
Leksawasdi, N., Breuer, M., Hauer, B., Rosche, B. and Rogers, P. (2003)
Kinetics of pyruvate decarboxylase deactivation by benzaldehyde
Biocat Biotrans.  21: 315-320
Rosche B, Breuer M, Hauer B, & Rogers P (2003)
Increased pyruvate efficiency in enzymatic production of (R)-phenylacetylcarbinol
Biotech Letters 25: 847‑851
Rosche, B., Breuer, M., Hauer, B. and Rogers, P. (2003)
Sreening of yeast for enzymatic (R)-phenylacetylcarbinol production
Biotech Letters. 25: 841-845