Associate Professor Vincent Murray
- Position: Associate Professor
- Room: 208A, Biological Sciences
- Phone: (+61 2) 9385 2028
- Fax: (+61 2) 9385 1483
- email: v.murray@unsw.edu.au
Professional Experience
- Cancer Institute, Melbourne 1982-1990
- Princeton University 1980-1982
Research Contribution
I have been an active researcher in the field of molecular biology for 30 years. My lab has concentrated on five areas in the last 10 years:-
My lab has made significant research contributions as shown by publication of over 65 papers in high profile international refereed journals. One of my Nucleic Acids Research articles has been cited over 400 times. In addition, 13 of my papers have been cited more than 30 times. I have published 3 papers in the Journal of Biological Chemistry (impact factor - 5.8) and 8 in Nucleic Acids Research (impact factor - 6.3).
I have given seminars at 19 international and local conferences and seminar series and have helped to organise 4 conferences. I have recently been invited to speak at the 6th Annual Congress of International Drug Discovery Science and Technology at Beijing, China in October 2008
Active Research Projects
- Development of More Effective Anti-cancer Drugs Based on Cisplatin
- Mechanism of Action of the Anti-tumour Drug Cisplatin
Publications
- Galea, A. M. & Murray, V. (2008)
- The Anti-tumour Agent, Cisplatin, and its Clinically Ineffective Isomer, Transplatin, Produce Unique Gene Expression Profiles in Human Cells.
- Cancer Informatics 6, 1–41.
- Cairns, M. J., McFadyen, W. D. & Murray, V. (2008)
- The DNA sequence selectivity of maltol-containing cisplatin analogues in purified plasmid DNA and in intact human cells.
- J. Inorgan. Biochem.,
- White, J., McFadyen, W. D., Carland, M., Denny, W. A. & Murray, V. (2006)
- 9,9a-diphenyl-1,3,4,6,7,9a-hexahydro-2H-pyrazino[1,2-a]pyrimidine at 130 K.
- Acta Crystallographica E62, o1846-o1848
- Temple, M. D. & Murray, V. (2005)
- Footprinting the 'essential regulatory region' of the retinoblatoma gene promoter in intact human cells
- International Journal of Biochemistry and Cell Biology 37, 665-678
- Carland, M., Tan, K. J., White, J. M., Stephenson, J., Murray, V., Denny, W. A. & McFadyen, W. D. (2005)
- Syntheses, crystal structure and cytotoxicity of diamine platinum(II) complexes containing maltol
- J. Inorg. Biochem. 99, 1738-1743
- Carland, M., Abrahams, B., Denny, W. A., Murray, V. & McFadyen, W. D. (2005)
- Hydrogen-bonded networks from novel platinum(II) dimers
- CrystEngComm 7, 701-705.
- Temple, M. D., Freebody, J. & Murray, V. (2004)
- Genomic and phylogenetic footprinting at the epsilon-globin silencer region in intact human cells
- Biochim. Biophys. Acta 1678, 126-134
- Davies, N. P., Freebody, J. & Murray, V. (2004)
- Chromatin structure at the flanking regions of the human beta globin locus control region DNase I hypersensitive site-2: Proposed nucleosome positioning by DNA-binding proteins including GATA 1
- Biochim. Biophys. Acta 1679, 201-213
- Robillard, M. S., Davies, N. P., van der Marel, G. A., van Boom, J. H., Reedijk, J. & Murray, V. (2003)
- The interaction of peptide-tethered platinum(II) complexes with DNA.
- J. Inorgan. Biochem. 96, 331-338