Associate Professor Robert Yang has been studying the biogenesis and dynamics of lipid droplets for over a decade.
Investigation of the Importance of Multiple Strains in H. pylori Infection
The bacterium Helicobacter pylori is a significant stomach pathogen of humans and has been causally linked to the development of gastritis, peptic ulcer disease (PUD) and gastric cancer (GC). Although 50% of the world’s population is infected with H. pylori, only a small percentage develops PUD and GC. The variable response to infection has led to a search for cofactors that modulate the risk of disease outcomes in infected individuals.
Current studies suggest that some patients may be infected with multiple strains of H. pylori. It is unclear however how commonly this occurs and whether the presence of multiple strains results from multiple infections or from changes in the initial infecting strain. This study will investigate the prevalence of multiple strain carriage in previously collected strains of H. pylori from patients with gastritis and gastric cancer. Where multiple strains are present, the similarity of the genetic makeup of these different strains. The project will include the use of cultural and molecular techniques.
BABS personnel that are responsible for this project