Dr. Ruiting Lan's use of minimum-spanning trees has enabled detailed analysis of the diversity of Bordatella pertussis genotypes in Australia.
Characteristics of Restriction Modification Enzyme Present in Zymomonas Mobilis
Since the whole genomic sequence of Zymomonas mobilis was published in 2005, interest in this bacterium has turned to metabolic engineering for biofuels and value-adding fermentation products. We propose to develop this bacterium as a novel platform host for metabolic engineering for biofuels and value-adding products.
This project will investigate the characteristics of restriction modification enzymes discovered in Zymomonas mobilis. In particular, to facilitate metabolic engineering of this bacterium there is a need to develop a lab-friendly version of the bacterium that has a reduced ability for restriction of foreign DNA, therefore allowing its transformation.
In this project, we will carry out heterologous expression of these enzymes and gene inactivation studies.
BABS personnel that are responsible for this project