The School of Biotechnology and Biomolecular Sciences at UNSW

The University of New South Wales

A leading research and teaching school with expertise in biotechnology, molecular biology, genetics, environmental microbiology, medical microbiology, immunology, biochemistry, protein chemistry and other areas of biological science.

Development of Polymer Nanoparticles for Tumor Chemotherapy

One of the most critical problems in cancerous tumour treatment is the lack of selective toxicity against tumour tissues. We aim to develop polymeric nanoparticles as anti-tumour drug delivery systems to eliminate non-selective toxicity of anticancer agents.

This project is a multidisciplinary research collaboration between BABS and CCIA <http://www.ccia.org.au> and includes an honours project for in-vitro evaluation of anticancer drug-loaded nanoparticles using human tumor cell cultures. It makes use of bioconjugation techniques, drug loading and release assays, cell culture, cell toxicity assays, flow cytometry and fluorescent microscopy. This program employs anti-cancer nanomedicines focusing on functional polymeric biomaterials and tumour chemotherapy.

BABS personnel that are responsible for this project