Gene Profiling Patients with Sepsis

Patients admitted to intensive care units usually have multiple co-morbid conditions, in particular sepsis. It is difficult to diagnose sepsis because it is a cascade of inflammatory events as well as clotting in blood vessels throughout the body in response to infection.

We are currently profiling gene expression in order to help clinicians to identify factors to diagnose these patients. The nature of this research project can be either applied or basic biology or both. Clinicians and researchers will develop a predictive gene cluster using a series of approaches including microarrays technology and quantitative RT-PCR to identify patients with suspected progression to sepsis.

The aim of this project is to develop techniques to assist in the management of patients in a life and death situation. This project has emphasis in both biology and bioinformatics.

BABS personnel responsible for this project:

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