Professional Experience

• 1987-1993 Prof & Chairman, Department of General Marine Microbiology, University of Göteborg (Sweden)
• 1981-1982 Research Fellow, University of Göteborg (Sweden)
• 1983-1986 Researcher, Swedish Natural Science Research Council

Research Contribution

At University of Goteborg, I established leading research programs in the areas of bacterial starvation and stress responses, microorganisms and interfaces, and marine biofouling. Strong European wide involvements included the biology of stasis in bacteria and risk assessment of deliberate release and the establishment of biological containment of genetically modified microorganisms.

At UNSW I have established an internationally recognised centre, CMB, which conducts basic and applied science in the areas of bacterial biofilms, cell-cell signalling, chemically mediated interactions between marine bacteria and sessile eukaryotes, novel marine bioactives, microbial environmental genomics, functional metagenomics, and bioremediation. A comprehensive set of patent families was licensed from the University to the biotechnology start up Biosignal Pty Ltd. The Environmental Microbiology Initiative, established in collaboration with Rick Cavicchioli and Brett Neilan will aid in building excellence in environmental genomics applied to research themes in environmental health and sustainability, water quality and water reuse, microbial processes and climate change, biodiversity and bioprospecting.

Honours & Awards

• Elected fellow of the Fellow of the American Academy of Microbiology
• Division Lecturer of the American Society of Microbiology
• Chair of the Scientific Advisory Board & Research Director, Biosignal Pty Ltd
• Vice President and President of the International Society of Microbial Ecology (ISME)
• Member of the Genetic Manipulation Advisory Committee
• Chairperson of the National Swedish Environmental Protection Board program
• Committee "Risk assessment of genetically modified organisms"
• Member of the Royal Swedish Academy of Science committee of Biology and Oceanography
• President of the Swedish Society of Microbiology
• Member of the Editorial Board of Microbes and the Environment, ISME Journal, Environmental Microbiology, Journal Biologia, Microbiology (UK), Molecular Marine Biology & Biotechnology, Ophelia, FEMS Microbiology Reviews, Applied and Environmental Microbiology, Journal of Microbiological Methods

Active Research Projects

• Bioactive Natural Products from Marine Surface-Associated Bacteria
• Copiotrophy vs. Oligotrophy in the Marine Environment
• Electron Shuttles for Degradation of Chlorinated Pollutants
• Experimental Evolution - Characterising Group Selection
• Functional Diversity of HOst-associated Marine Bacteria
• Genetic Heterogeneity of Natural Marine Microbial Population
• Host Interaction and Virulence in Marine Bacteria
• Identification of Inducers of Settlement of Invertebrate Larvae
• Increased Virulence, Survival and Fitness of Mixed Bacterial Communities
• Protozoan Grazing and Chemical Defence
• Regulation of Biofilm Formation and Anti-protozoal Activity of Vibrio Cholerae
• Signalling Pathways Involved in Biofilm Development and Dispersal
• To Eat or Not to Eat: The Molecular Bases of Sponge-Bacteria Symbiosis

Publications

Bernbom, N., Yoke, Y.Y., Kjelleberg, S., Harder, T. & Gram, L. (2011)
Marine bacteria from Danish coastal waters show antifouling activity against the marine fouling bacterium Pseudoalteromonas S91 and zoospores of the green alga Ulva australis independent of bacteriocidal activity.
Applied and Environmental Microbiology, epub ahead of print. doi 10.1128/AEM.06038-11

Jayawardena, M.B., Yee, L.H., Rainbow, I.J., Bergquist, P., Such, C.H., Steinberg, P.D. & Kjelleberg, S. (2011)
Surfactant enhanced lipase containing films characterized by confocal laser scanning microscopy.
Colloids and Surfaces B – Biointerfaces. 82(2): 291-296.

Erken, M., Weitere, M., Kjelleberg, S. & McDougald, D. (2011)
In situ grazing resistance of Vibrio cholerae in the marine environment.
FEMS Microbiology Ecology. 76(3): 504-512.

Burke, C.M., Steinberg, P.D., Rusch, D., Kjelleberg, S. & Thomas, T. (2011)
Bacterial community assembly based on functional genes rather than species.
Proceedings of the National Academy of Sciences of the United States of America. 108(34): 14288-14293.

Kumar, V., Rao, D., Thomas, T., Kjelleberg, S. & Egan, S.G. (2011)
Antidiatom and antibacterial activity of epiphytic bacteria isolated from Ulva lactuca in tropical waters.
World Journal of Microbiology and Biotechnology. 27(7): 1543-1549.

Anderson, R., Kjelleberg, S., McDougald, D. & Jurgens, K. (2011)
Species-specific patterns in the vulnerability of carbon-starved bacteria to protist grazing.
Aquatic Microbial Ecology. 64(2): 105-116.

Liu, M.Y., Kjelleberg, S. & Thomas, T. (2011)
Functional genomic analysis of an uncultured delta-proteobacterium in the sponge Cymbastela concentrica.
ISME Journal. 5(3): 427-435.

Burke, C.M., Thomas, T., Lewis, M., Steinberg, P.D. & Kjelleberg, S. (2011)
Composition, uniqueness and variability of the epiphytic bacterial community of the green alga Ulva australis.
ISME Journal. 5:590-600.

Penesyan, A., Tebben, J., Lee, M., Thomas, T., Kjelleberg, S. & Egan, S. (2011)
Identification of the antibacterial compound produced by the marine epiphytic bacterium Pseudovibrio sp. D323 and related sponge-associated bacteria.
Marine Drugs. 9: 1391-1402.

Fernandes, N., Case, R.J., , Longford, S.R., Steinberg, P.D., Kjelleberg, S. & Thomas, T. (2011)
Genomes and virulence factors of novel bacterial pathogens causing bleaching disease in the marine red alga Delisea pulchra.
PLoS ONE. 6(9): e27387. doi:10.1371/journal.pone.0027387

Case, R.J., Longford, S.R., Campbell, A.H., Low, A., Tujula, N.A., Steinberg, P.D. & Kjelleberg, S. (2011)
Temperature induced bacterial virulence and bleaching disease in a chemically defended marine macroalga.
Environmental Microbiology. 13(2): 529-537.

Campbell, A.H., Harder, T., Nielsen, S., Kjelleberg, S. & Steinberg, P.D. (2011)
Climate change and disease: Bleaching of a chemically defended seaweed.
Global Change Biology. 17(9): 2958-2970.

Yung, P.Y., Kjelleberg, S. & Thomas, T. (2011)
A polyphasic approach to the exploration of collagenolytic activity in the bacterial community associated with the marine sponge Cymbastela concentrica.
FEMS Microbiology Letters. 321(1): 24-29.

Schleheck, D.F., Weiss, M., Pitluck, S., Bruce, D., Land, M.L., Han, S., Tapia, R., Detter, C.C.C., Brettin, T., Han, J., Woyke, T., Goodwin, L., Pennacchio, P., Nolan, M., Cook, A.M., Kjelleberg, S. & Thomas, T. (2011)
Complete genome sequence of Parvibaculum lavamentivorans type strain (DS-1T).
Standards in Genomic Sciences. 5(3)  doi:10.4056/sigs.2215005

Ballestriero, F., Thomas, T., Burke, C.M., Egan, S.G., & et al. (2010)
Identification of Compounds with Bioactivity against the Nematode Caenorhabditis elegans by a Screen Based on the Functional Genomics of the Marine Bacterium Pseudoalteromonas tunicata D2.
Applied and Environmental Microbiology. 17: 5710-5717.

Burke, CM, Torsten, T, Lewis, M, Steinberg, PD, & et al. (2010)
Composition, uniqueness and variability of the epiphytic bacterial community of the green alga Ulva australis.
The ISME Journal. Epub ahead of print: 5710-5717. doi:10.1038/ismej.2010.164

Moreno, A., Matz, C., Kjelleberg, S., & Manefield, M.J. (2010)
Identification of ciliate grazers of autotrophic bacteria in ammonia-oxidizing activated sludge by RNA stable isotope probing.
Applied and Environmental Microbiology. 76: 2203-2211.

Moreno, A., Matz, C., Kjelleberg, S., & Manefield, M.J. (2010)
RNA stable isotope probing identifies ciliate grazer of autotrophic bacteria in ammonia-oxidizing activated sludge.
Applied and Environmental Microbiology. 76: 115-117.

Penesyan, A., Kjelleberg, S., & Egan, S.G. (2010)
Development of Novel Drugs from Marine Surface Associated Microorganisms.
Marine Drugs. 8: 428-459.

Thomas, T., Rusch, D., De Maere, M., Yung, P.Y., et al. (2010)
Functional genomic signatures of sponge bacteria reveal unique and shared features of symbiosis.
ISME JOURNAL. 4: 1557-1567.

Tujula, N.A., Crocetti, G.R., Burke, C.M., Thomas, T., et al. (2010)
Variability and abundance of the epiphytic bacterial community associated with a green marine Ulvacean alga.
ISME JOURNAL. 4: 301-311.

Yee, L.H., Aagaard, V., Johnstone, A., Lee, M., et al. (2010)
Development of a treatment solution for reductive dechlorination of hexachloro-1,3-butadiene in vadose zone soil.
Biodegradation. 21: 947-956.

Zhou, Y., Ganda, L., Lim, M., Yuan, Z., et al. (2010)
Free nitrous acid (FNA) inhibition on denitrifying poly-phosphate accumulating organisms (DPAOs).
Applied Microbiology and Biotechnology. 88: 359-369.

Barraud, N., Schleheck, D.F., Klebensberger, J., Webb, J., et al. (2009)
Nitric oxide signaling in Pseudomonas aeruginosa biofilms mediates phosphodiesterase activity, decreased cyclic diguanosine-5'-monophosphate levels and enhanced dispersal.
Journal of Bacteriology. 191: 7333-7342.

Barraud, N., Storey, M., Moore, Z.P., Webb, J., et al. (2009)
Nitric oxide-mediated dispersal in single- and multi-species biofilms of clinically and industrially relevant microorganisms.
Microbial Biotechnology. 2: 370-378.

Burke, C.M., Kjelleberg, S., & Thomas, T. (2009)
Selective extraction of bacterial DNA from the surfaces of macroalgae.
Applied and Environmental Microbiology. 75: 252-256.

Klebensberger, J., Birkenmaier, A., Geffers, R., Kjelleberg, S., & et al. (2009)
SiaA and SiaD are essential for inducing autoaggregation as a specific response to detergent stress in Pseudomonas aeruginosa.
Environmental Microbiology. 11: 3073-3086.

Lauro, F.M., McDougald, D., Thomas, T., Williams, T.J., et al. (2009)
The genomic basis of trophic strategy in marine bacteria.
Proceedings of the National Academy of Sciences of the United States of America - Biological Sciences. 106: 15527-15533.

Manos, J., Arthur, J.F., Rose, B., Bell, S., et al. (2009)
Gene expression characteristics of a cystic fibrosis epidemic strain of Pseudomonas aeruginosa during biofilm and planktonic growth.
FEMS Microbiology Letters. 292: 107-114.

Penesyan, A., Marshall-Jones, Z., Holmstrom, C.G., Kjelleberg, S., & et al. (2009)
Antimicrobial activity observed among cultured marine epiphytic bacteria reflects their potential as a source of new drugs.
FEMS Microbiology Ecology. 69: 113-124.

Rice, S.A., Tan, C., Mikkelsen, P., Kung, V., et al. (2009)
The biofilm life cycle and virulence of Pseudomonas aeruginosa are dependent on a filamentous prophage.
ISME JOURNAL. 3: 271-282.

Schleheck, D.F., Barraud, N., Klebensberger, J., Webb, J., et al. (2009)
Pseudomonas aeruginosa PAO1 preferentially grows as aggregates in liquid batch cultures and disperses upon starvation.
PLOS One. 4: p.e5513.

Yung, P.Y., Burke, C.M., Lewis, M., Egan, S.G., et al. (2009)
Phylogenetic screening of a bacterial, metagenomic library using homing endonuclease restriction and marker insertion.
Nucleic Acids Research. 37: e144 - 3485.

Evans, F.F., Egan, S. and Kjelleberg, S. (2008)
Ecology and Gene composition of Type II secretion in marine gamma proteobacteria
Environmental Microbiology 10:1101-1107

Egan, S., Thomas, T. and Kjelleberg, S. (2008)
Unlocking the diversity and biotechnological potential of marine surface associated microbial communities.
Current Opinion in Microbiology, (in press May 2008)

Mai-Prochnow A, Lucas-Elio P, Egan S, Thomas T, Webb JS, Sanchez-Amat A, Kjelleberg S (2008)
Hydrogen peroxide linked to lysine oxidase activity facilitates biofilm differentiation and dispersal in several Gram negative bacteria
Journal of Bacteriology. 2008 May 23.

Case, R.J., Labbate, M. and Kjelleberg, S. (2008)
AHL-driven quorum-sensing circuits: their frequency and function among the Proteobacteria.
ISME Journal. 2: 345-349

Huggett, M.J., Crocetti, G.R., Kjelleberg, S. and Steinberg, P.D. (2008)
Recruitment of the sea urchin Heliocidaris erythrogramma and the distribution and abundance of inducing bacteria in the field.
Aquatic Microbial Ecology. 53: 161-171

Kjelleberg, S., McDougald, D., Rasmussen, T.B. and Givskov, M. (2008)
Quorum sensing inhibition
In: Chemical Communication Among Bacteria. Winans SC and Bassler BL (Eds). ASM Press, Washington D.C., pp 393-416

Manos J, Arthur J, Rose B, Tingpej P, Fung C, Curtis M, Webb JS, Hu HH, Kjelleberg S, Gorrell MD, Bye P and Harbour C. (2008)
Transcriptome analyses and biofilm-forming characteristics of a clonal Pseudomonas aeruginosa from the cystic fibrosis lung.
Journal of Medical Microbiology. 57: 1454-1465.

Huggett MJ, Crocetti GR, Kjelleberg S and Steinberg PD. (2008)
Recruitment of the sea urchin Heliocidaris erythrogramma and the distribution and abundance of inducing bacteria in the field.
Aquatic Microbial Ecology. 53: 161-171

Matz, C., Moreno, A.M., Alhede, M., Manefield, M, Hauser, A.R., Givskov, M and Kjelleberg, S. (2008)
Pseudomonas aeruginosa uses type III secretion system to kill biofilm-associated amoebae.
ISME Journal. 2: 843-852.

Matz, C., Webb, J.S., Schupp, P.J., Phang, S.Y., Penesyan, A., Egan, S., Steinberg, P. and Kjelleberg, S. (2008)
Marine biofilm bacteria evade eukaryotic predation by targeted chemical defense.
PLoS One. 3: e2744

McDougald, D., Klebensberger, J., Tolker-Nielsen, T., Webb, J.S., Conibear, T., Rice, S., Kirov, S. and Kjelleberg, S. (2008)
Pseudomonas aeruginosa: a model for biofilm formulation.
In: Pseudomonas. Modal Organism, Pathogen, Workhorse. Rehm B (Eds). WILEY-VCH Verlag GmbH and Co, Weinheim, pp 215-253.

Platt MD, Schurr MJ, Sauer K, Vazquez G, Kukavica-Ibrulj I, Potvin E, Levesque RC, Fedynak A, Brinkman FSL, Schurr J, Hwang SH, Lau GW, Limbach PA, Rowe JJ, Lieberman MA, Barraud N, Webb J, Kjelleberg S, Hunt DF and Hassett DJ. (2008)
Pseudomonas aeruginosa at pH 6.5, likely representing chronic, late-stage cystic fibrosis airway conditions.
Journal of Bacteriology. 190: 2739-2758

Rice, S.A., McDougald, D., Givskov, M. and Kjelleberg, S. (2008)
Detection and inhibition of bacterial cell-cell communication.
In: Bacterial Pathogenesis: Methods and Protocols. DeLeo F and Otto M (Eds). Humana Press Inc, Totowa, NJ, pp

Thomas, T., Evans, F.F., Schleheck, D., Mai-Prochnow, A., Burke, C., Penesyan, A., Dalisay, D.S., Stelzer-Braid, S., Saunders, N., Johnson, J., Ferriera, S., Kjelleberg, S. and Egan, S. (2008)
Analysis of the Pseudoalteromonas tunicata genome reveals properties of a surface-associated life style in the marine environment.
PLoS One. 3: e3252.

Willcox, M.D.P., Zhu, H., Conibear, T.C.R., Hume, E.B.H., Givskov, M., Kjelleberg, S. and Rice, S.A. (2008)
Role of quorum sensing by Pseudomonas aeruginosa in microbial keratitis and cystic fibrosis.
Microbiology-SGM. 154: 2184-2194.

McDougald, D., Klebensberger, J., Tolker-Nielsen, T., Webb, J.S., et al. (2008)
Pseudomonas: Model Organism, Pathogen, Cell Factory.
In: Pseudomonas: Model Organism, Pathogen, Cell Factory. WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany.

Platt, M., Schurr, M., Sauer, K., Vazquez, G., et al. (2008)
Proteomic, microarray, and signature-tagged mutagenesis analyses of anaerobic Pseudomonas aeruginosa at pH 6.5, likely representing chronic, late-stage cystic fibrosis airway conditions.
Journal of Bacteriology. 190: 2739-2758.

Battin, T.J., Sloan, W.T., Kjelleberg, S., Daims, H., Head, I.M., Curtis, T.P. & Eberl, L. (2007)
Microbial landscapes: New paths to biofilm research.
Nature Reviews Microbiology. 5: 76-81.

Burke, C.,  Thomas, T.,  Egan, S. and Kjelleberg, S (2007)
The use of functional genomics for the identification of an antifungal gene cluster in the epiphytic marine bacterium Pseudoalteromonas tunicata
Environmental Microbiology, 9:814-818

Evans, F.F.,  Raftery, M.J.,  Egan, S. and Kjelleberg, S. (2007)
Profiling the secretome of the marine bacterium Pseudoalteromonas tunicata using amine-specific isobaric tagging (iTRAQ)
Journal of Proteome Research, 6:967-75.

Yee, L.H., Holmstrom, C., Fuary, E.T., Lewin, N.C., Kjelleberg, S., Steinberg, P.D. (2007)
Inhibition of fouling by marine bacteria immobilised in k-carrageenan beads
Biofouling, 23:4, 287-294

Kjelleberg, S., & Givskov, M. (ed) (2007)
The Biofilm Mode of Life: Mechanisms and Adaptations.
Horizon Bioscience, Norfolk UK.

Rice, S.A., McDougald, D., Givskov, M.G., & Kjelleberg, S. (2007)
Bacterial Pathogenesis.
In: Bacterial Pathogenesis. Humana Press, Totowa, NJ USA.

Case, R.J., Boucher, Y., Dahllof, I., Holmstrom, C.G., et al. (2007)
Use of 16S rRNA and rpoB genes as molecular markers for microbial ecology studies.
Applied and Environmental Microbiology. 73: 278-288.

Christensen, L., Moser, C., Jensen, P., Rasmussen, T.B., et al. (2007)
Impact of Pseudomonas aeruginosa quorum sensing on biofilm persistence in an in vivo intraperitoneal foreign-body infection model.
Microbiology - SGM. 153: 2312-2320.

Kirov, S.M., Webb, J.S., O`May, C., Reid, D., et al. (2007)
Biofilm differentiation and dispersal in mucoid Pseudomonas aeruginosa isolates from patients with cystic fibrosis.
Microbiology - SGM. 153: 3264-3274.

Koh, K.S., Lam, K.W., Alhede, M., Queck, S.Y., et al. (2007)
Phenotypic diversification and adaptation of Serratia marcescens MG1 biofilm-derived morphotypes.
Journal of Bacteriology. 189: 119-130.

Labbate, M., Zhu, H., Thung, L., Bandara, R., et al. (2007)
Quorum-sensing regulation of adhesion in Serratia marcescens MG1 is surface dependent.
Journal of Bacteriology. 189: 2702-2711.

Longford, S.R., Tujula, N.A., Crocetti, G.R., Holmes, A., et al. (2007)
Comparisons of diversity of bacterial communities associated with three sessile marine eukaryotes.
Aquatic Microbial Ecology. 48: 217-229.

McDougald, D., Rice, S.A., & Kjelleberg, S. (2007)
Bacterial quorum sensing and interference by naturally occurring biomimics.
Analytical and Bioanalytical Chemistry. 387: 445-453.

Mueller, R., McDougald, D., Cusumano, D., Sodhi, N., et al. (2007)
Vibrio cholerae strains possess multiple strategies for abiotic and biotic surface colonization.
Journal of Bacteriology. 189: 5348-5360.

Skovhus, T.L., Holmstrom, C.G., Kjelleberg, S., & Dahlloef, I. (2007)
Molecular investigation of the distribution, abundance and diversity of the genus Pseudoalteromonas in marine samples.
FEMS Microbiology Ecology. 61: 348-361.

Kjelleberg, S., & Rice, S.A. (2007)
The slippery business of slime control.
Microbiology Australia. 28: 118 - 120.