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Ian Dawes

Professor Ian Dawes

BSc (UNSW) DPhil (Oxford)

Scientia Professor

Room No:

202

Office:

Room 202, Biological Sciences

Phone:

9385 2089

Fax:

9385 1050

Email:

i.dawes@unsw.edu.au
Teaching Responsibilities:

BIOC3121  Course Lecturer
BIOC3151  Course Lecturer
MICR3021/3261  Course Lecturer
BIOC3281  Course Lecturer
BIOC3291  Course Lecturer
BIOS1201  Course Lecturer
BIOS2021/2621  Course Lecturer
   
   
   
   

Research Description:

Regulation of gene expression, functional genomics and systems biology. We study the mechanisms whereby cells regulate gene expression under a range of important conditions including cellular responses to oxidative stress, cell differentiation, control of one-carbon metabolism, and pre-mRNA splicing. This involves a combined molecular, genomic and biochemical approach. It uses microarray and high throughput robotic techniques widely and has direct access to the genome-wide set of yeast deletion mutants.

Selected Publications:

Alic, N., Higgins, V.J. and Dawes, I.W. (2001). Identification of a Saccharomyces cerevisiae gene that is required for G1 arrest in response to the lipid oxidation product linoleic acid hydroperoxide. Mol. Biol. Cell 10, 1801-1810.

Laun, P., Pichova A., Madeo, F., Fuchs, J., Ellinger, A., Kohlwein, S., Dawes, I., Fröhlich, K-U. & Breitenbach, M. (2001). Aged mother cells of S. cerevisiae show markers of oxidative stress and apoptosis. Molec. Microbiol., 39, 1166-1173.

Higgins, V.J., Alic, N., Thorpe, G.W., Breitenbach, M., Larsson, V. and Dawes, I.W. (2002). Phenotypic analysis of gene deletant strains for sensitivity to oxidative stress. Yeast, 19, 203-214.

Piper, M.D., Hong, S.P., Ball, G.E. and Dawes I.W. (2000). Regulation of the balance of one-carbon metabolism in Saccharomyces cerevisae. J. Biol. Chem. 275, 30987-30995.
Other Professional Activities:

Member of Editorial Boards: Journal of General Microbiology (1980-86); Yeast (1985- ); Molecular Microbiology (1989-1996); FEMS Yeast Research (2000-), Deputy Director of CRC for Food Industry Innovation (1994-2000 ), Member ARC Molecular and Cellular Biology Grant Review Panel (1994-6), Deputy Chair of ARC Biological Sciences Large Grants Panel (1995-6), Member ARC Research Grants Committee (1995-6), Chairman, Lorne Genome Conference (1995), Member Scientific Program Committees for 7th FAOBMB Congress (Sydney, 1995), 17th Int. Specialised Symposium on Yeasts (Edinburgh, 1995), 9th Int. Yeast Symposium (Sydney, 1996), 5th Asian Conference on Transcription (Lorne, 1998) Member, ARC Committee on Early Career Researchers (1995). Chair of ARC Biological Sciences Review Steering Committee (1996-7), Member of the Board of the Victor Chang Cardiac Research Institute (1996-), President of Lorne Genome Conference Inc. (1997-2000) and Board member (2000-), Member NSW Rhodes Scholarship Selection Committee (1997), Member ASBMB Research Committee (1998-2000), Member Int. Organising Committee Asian Conferences on Transcription (2000-), Member Steering Committee for Australian Centre for Plant Functional Genomics (2001-) Chairman of the International Conferences on Yeast Genetics and Molecular Biology (2001-8), President-elect Society for Free Radical Research (Australasia) (2001-
 


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