| |
|
|
Research Staff Contact Details
|
Dr Ruby C Y Lin
|
|
PhD, MSc (Hons), BSc
|
|
NHMRC Peter Doherty Fellow
|
|
Room No:
|
131, Ramaciotti Centre
|
|
Office:
|
Ramaciotti Centre for Gene Function Analysis, School of Biotechnology and Biomolecular Sciences (D26), University of New South Wales, NSW 2052, Australia
|
|
Phone:
|
9385 1241 (office)
9385 1658 (lab)
|
|
Fax:
|
9385 1277
|
|
Email:
|
rubyl@unsw.edu.au
|
Research Description:
Research interests include functional genomics and comparative genomics involving human subjects, rodent models and mammalian cell lines, with specific focus on cardiovascular diseases and related disorders. The lab has knowledge and experience in high throughput technology, molecular genetics, molecular biology and resources for bioinformatics. Current projects include: defining transcriptional homeostasis using mammalian cell lines and yeast deletion mutant models, premature ageing in cardiomycytes using rodent models, pathological hypertrophy in rodent models, and investigating regulons involved in cellular aging.
Selected Publications:
|
Lin RCY, Wang XL, Morris BJ. Association of coronary artery disease with glucocorticoid receptor N363S variant. Hypertension 2003;41:404-407
|
|
Lin RCY, Schyvens C, Zhang Y, Whitworth JA, Morris BJ. The role of tumor necrosis factor 2 (Tnfr2) in the pathogenesis of hypertension in the rat. American Journal of Hypertension 2003;16:685-688
|
|
Lin RCY, Wang WYS, Morris BJ. Overweight conferred by highly penetrant glucocorticoid receptor variant: a case-control study. British Medical Journal 1999;319:1337-1338
|
|
Lin RCY, Wang WYS, Morris BJ. Association and linkage of glucocorticoid receptor gene markers in essential hypertension. Hypertension 1999;34:1186-1192
|
|
Tang BMP, McLean AS, Dawes IW, Huang SJ, Lin RCY. The use of gene-expression profiling improves diagnosis of sepsis. American Journal of Respiratory and Critical Care Medicine 2007;176:676-684. Editorial: Moldawer LL. Opening the window on genome-wide expression analyses in sepsis. Am J Respir Crit Care Med 2007:176:631-635.
|
|
Stephani M, Markus MA, Lin RCY, Dawes IW, Morris BJ. The effect of resveratrol on an in vitro model of human ageing. Annals of The New York Academy of Sciences 2007 2007;1114:407-418.
|
Other Professional Activities:
Member of NSW Cardiovascular Club Australia,
Member of High Blood Pressure Research Council of Australia,
Member of Australian Society for Medical Research
Co-Chair of Common Interest Group in Genetics and Genomics, BABS, UNSW
Member of The Endocrine Society of Australia
Member of Australasian Microarray & Associated Technologies Association (AMATA)
|
|
