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Academic Staff Contact Details
Vincent Murray

A/Professor Vincent Murray

PhD

Associate Professor

Room No:

208A

Office:

Room 208A (enter via room 210), 2nd floor, Biological Sciences Building

Phone:

9385 2028

Fax:

9385 1483

Email:

v.murray@unsw.edu.au
Teaching Responsibilities:

BIOC2201  Course Coordinator
BIOC3121  Course Lecturer
BIOC3281  Course Lecturer
BIOC2291  Course Lecturer
 

Research Description:

1) The influence of chromatin structure on the control of gene expression; 2) The DNA sequence specificity of drugs used as cancer chemotherapeutic agents; 3) The development of more efficient anti-tumour agents based on cisplatin; 4) The use of gene chip microarrays to examine the effects of anti-tumours agents on gene expression; 5) The use of the human papillomavirus promoter to preferentially target gene therapy to cervical cancer cells.

Selected Publications:

Temple, M. D., McFadyen, W. D., Holmes, R. J., Denny, W. A. & Murray, V. (2000). The interaction of cisplatin and DNA-targeted 9-aminoacridine platinum complexes with DNA. Biochemistry 39, 5593-5599.

Davies, N. P., Hardman, L. C. & Murray, V. (2000). The effect of chromatin proteins on cisplatin damage in intact human cells. Nucl. Acids. Res. 28, 2954-2958.

Galea, A. & Murray, V. (2002). Cisplatin preferentially targets the linker region of the nucleosome. Biochim. Biophys. Acta 1579, 142-152.

Murray, V. (2000). A survey of the sequence-specific interaction of damaging agents with DNA: emphasis on anti-tumour agents. (Review). Prog. Nucl. Acid Res. Mol. Biol. 63, 367-415.
 


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