Dr Iryna Leshchysn'ka

Position: 
Postdoctoral Research Associate (Sytnyk Lab)
Room: 
Level 3 West, Bioscience South E26
Telephone: 
(+61 2) 9385-1108
Fax: 
(+61 2) 9385-1483


Research Contribution

Cell adhesion molecules are crucial for the development and functioning of the nervous system. In developing neurons, cell adhesion molecules of the immunoglobulin superfamily accumulate in growth cones. In response to activation by their ligands, e.g. proteins of the extracellular matrix or adhesion molecules on adjacent cells, cell adhesion molecules induce assembly of the signalling complexes which are important for the neuronal growth and differentiation. In differentiated neurons, cell adhesion molecules accumulate in synapses and promote their structural stability and activity.

Our research is focused on further clarification and understanding of the molecular mechanisms mediated and regulated by cell adhesion molecule in developing and adult nervous tissues. We hope that this knowledge will help us to understand how mutations in cell adhesion molecules lead to abnormalities in neuronal development, establishment of neuronal networks, and synaptic transmission and inflict mental disorders.

Publications

Click here for Dr Leshchyns'ka's publications list