Dr Laura Sharpe
- 2011-present: Post-Doctoral Research Associate, School of BABS, UNSW
Determining the role of signalling and phosphorylation in cholesterol regulation, and identifying novel Akt targets.
Sharpe, L.J., Luu, W., & Brown, A.J. (2011)
Akt phosphorylates Sec24: New clues into the regulation of ER-to-Golgi trafficking.
Traffic (Malden. 12( 1): 19–27.
Sharpe, L.J., Eden, J-S., White, P.A. & Brown, A.J. (2011)
Norovirus RNA-dependent RNA polymerase is phosphorylated by an important survival kinase, Akt. Journal of Virology. 85(20): 10894–10898.
Krycer, J.R., Sharpe, L.J., Luu, W. & Brown, A.J. (2010)
The Akt-SREBP nexus: cell signaling meets lipid metabolism.
Trends in Endocrinology and Metabolism. 21: 268-278.
Kristiana, I., Sharpe, L.J., Catts, V.S., Lutze-mann, L.H. & Brown, A.J. (2010)
Antipsychotic drugs upregulate lipogenic gene expression by disrupting intracellular trafficking of lipoprotein-derived cholesterol.
Journal of Pharmacogenomics. 10(5): 396-407.
Sharpe, L.J. & Brown, A.J. (2008)
Rapamycin down-regulates LDL-receptor expression independently of SREBP-2.
Biochemical and Biophysical Research Communications. 373: 670-674.