Alison Velyian Todd

Adjunct Senior Lecturer

PUBLICATIONS

Journal articles
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Linardy EM; Erskine SM; Lima NE; Lonergan T; Mokany E; Todd AV, 2016, 'EzyAmp signal amplification cascade enables isothermal detection of nucleic acid and protein targets', Biosensors and Bioelectronics, vol. 75, pp. 59 - 66, http://dx.doi.org/10.1016/j.bios.2015.08.021
2016
Bone SM; Lima NE; Todd AV, 2015, 'DNAzyme switches for molecular computation and signal amplification', Biosensors and Bioelectronics, vol. 70, pp. 330 - 337, http://dx.doi.org/10.1016/j.bios.2015.03.057
2015
Bone SM; Hasick NJ; Lima NE; Erskine SM; Mokany E; Todd AV, 2014, 'DNA-only Cascade: A universal tool for signal amplification, enhancing the detection of target analytes', Analytical Chemistry, vol. 86, pp. 9106 - 9113, http://dx.doi.org/10.1021/ac501811r
2014
Bone SM; Todd AV, 2014, 'MNAzymes provide a universal mechanism for triggering DNAzyme synthesis cascades', Chemical Communications, vol. 50, pp. 13243 - 13246, http://dx.doi.org/10.1039/c4cc05919k
2014
Mitsuyasu RT; Merigan T; Carr AD; Zack J; Winters M; Workman C; Bloch MT; Lalezari J; Becker S; Thornton L; Akil B; Khanlou H; Finlayson R; Mcfarlane R; Smith DE; Garsia R; Ma DD; Law MG; Murray JM; Von Kalle C; Ely JA; Patino S; Knop A; Wong P; Todd A; Haughton M; Fuery C; Marcpherson J; Symonds G; Evans L; Pond SM; Cooper DA, 2009, 'Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34+ cells', Nature Medicine, vol. 15, pp. 285 - 292, http://dx.doi.org/10.1038/nm.1932
2009
Macpherson JL; Boyd MP; Arndt AJ; Todd AV; Ganning GC; Ely JA; Elliott F; Knop A; Raponi M; Murray JM; Gerlach W; Sun L; Penny R; Symonds GP; Carr AD; Cooper DA, 2005, 'Long-term survival and concomitant gene expression of ribozyme-transduced CD4+ T-lymphocytes in HIV-infected patients', Journal of Gene Medicine, vol. 7, pp. 552 - 564, http://dx.doi.org/10.1002/jgm.705
2005
Boyd MP; Ngok FK; Todd AV; Symonds GP; Macpherson JL; Amado RG, 2004, 'Critical steps in the implementation of hematopoietic progenitor-cell gene therapy using ribozyme vectors: a laboratory protocol.', Methods in molecular biology (Clifton, N.J.), vol. 252, pp. 599 - 616, http://dx.doi.org/10.1385/1-59259-746-7:599
2004
Amado RG; Mitsuyasu RT; Rosenblatt JD; Ngok FK; Bakker A; Cole S; Chorn N; Lin LS; Bristol G; Boyd MP; Macpherson JL; Fanning GC; Todd AV; Ely JA; Zack JA; Symonds GP, 2004, 'Anti-human immunodeficiency virus hematopoietic progenitor cell-delivered ribozyme in a phase I study: Myeloid and lymphoid reconstitution in human immunodeficiency virus type-1-infected patients', Human Gene Therapy, vol. 15, pp. 251 - 262, http://dx.doi.org/10.1089/104303404322886101
2004
Norrie M; Hawkins NJ; Todd AV; Meagher AP; O Connor TW; Ward RL, 2003, 'Inactivation of p16INK4a by CpG hypermethylation is not a frequent event in colorectal cancer', Journal of Surgical Oncology, vol. 84, pp. 143 - 150, http://dx.doi.org/10.1002/jso.10310
2003
Norrie M; Hawkins NJ; Todd AV; Meagher AP; O Connor TW; Ward RL, 2002, 'The role hMLH1 methylation in the development of solitary and synchronous sporadic colorectal carcinomas', Diseases of the Colon and Rectum, vol. 45, pp. 674 - 680, http://dx.doi.org/10.1007/s10350-004-6266-1
2002
Fuery CJ; Impey H; Roberts NK; Applegate TL; Ward RL; Hawkins NJ; Sheehan C; O Grady R; Todd AV, 2000, 'Detection of rare mutant alleles by restriction endonuclease-mediated selective-PCR: assay design and optimization', Clinical Chemistry, vol. 46, pp. 620 - 624
2000
Ward RL; Sheehan C; Norrie M; Applegate TL; Fuery CJ; Impey H; Hawkins NJ; Todd AV, 2000, 'Factors influencing the detection of mutant K-ras in the serum of patients with colorectal cancer', Annals of the New York Academy of Sciences, vol. 906, pp. 17 - 18, http://dx.doi.org/10.1111/j.1749-6632.2000.tb06583.x
2000
Todd AV; Adams A; Thorpe J; Denny WA; Wakelin L; Cardin CJ, 1999, 'Major groove binding and a `DNA-induced` fit in the intercalation of a derivative of the mixed topoisomerase I/II inhibitor (N-(2-dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU', Journal of Medicinal Chemistry, vol. 42, pp. 536 - 540, http://dx.doi.org/10.1021/jm980479u
1999
Todd AV; Adams A; Powell HK; Wilcock DJ; Thorpe JH; Lausi A; Zanini F; Wakelin L; Cardin CJ, 1999, 'Determination of MAD-DM of the structure of the DNA duplex d(ACGTACG(5-BrU)2 at 1.4 A and 100 K', ACTA Crystallographica Section D - Biological Crystallography, vol. 55, pp. 729 - 735, http://dx.doi.org/10.1107/S090744499801261X
1999
Roberts NJ; Impey H; Applegate TL; Furey C; Ward RL; Todd AV, 1999, 'Rapid and sensitive detection of mutant alleles in codon 12 of K-ras by restriction endonuclease-mediated selective polymerase chain reaction (REMS-PCR)', BioTechniques, vol. 27, pp. 418 - 422
1999
Ward RL; Hawkins NJ; O Grady R; Sheehan C; O Connor TW; Impey H; Furey C; Todd AV; Roberts N, 1998, 'Restriction endonuclease-mediated selective polymerase chain reaction. A novel assay for the detection of K-ras mutations in clinical samples.', American Journal of Pathology, vol. 153, pp. 373 - 379, http://dx.doi.org/10.1016/S0002-9440(10)65581-2
1998
Ward RL; Todd AV; Santiago FS; O Connor TW; Hawkins NJ, 1997, 'Activation of the K-ras oncogene in colorectal neoplasms is associated with decreased apoptosis', Cancer, vol. 79, pp. 1106 - 1113, http://dx.doi.org/10.1002/(SICI)1097-0142(19970315)79:6<1106::AID-CNCR8>3.0.CO;2-D
1997
Santiago FS; Todd AV; Hawkins NJ; Ward RL, 1997, 'Detection of K-ras point mutation by enriched PCR-colorimetric plate assay', Molecular and Cellular Probes, vol. 11, pp. 33 - 38, http://dx.doi.org/10.1006/mcpr.1996.0073
1997
Ward RL; Santiago FS; Hawkins NJ; Coomber DW; O Connor TW; Todd AV, 1995, 'A rapid PCR ELISA for the detection of activates K-ras in colorectal cancer', Journal of Clinical Pathology, vol. 48, pp. 273 - 277, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1995RZ58000009&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
1995