BABS Dr Vladimir Sytnyk's Discovery Possible New Treatments for Alzheimer's

Date: 
30/11/2015

Recent work being done by Senior Lecturer Dr Vladimir Sytnyk’s lab on Alzheimer's Disease has just been published in the prestigious journal Nature Communications. The study’s first author is Vladimir's Research Associate Dr Iryna Leshchyns’ka and the team includes researchers from Neuroscience Research Australia and the Dementia Research Unit of UNSW's School of Medical Sciences.

The project studied a protein in the brain called neural cell adhesion molecule 2, or NCAM2 – one of a family of molecules that physically connects the membranes of synapses and help stabilise these long lasting synaptic contacts between neurons. One of the first signs of Alzheimer’s disease is the loss of synapses. Using post-mortem brain tissue from people with and without the condition, they discovered that synaptic NCAM2 levels in the part of the brain known as the hippocampus were low in those with Alzheimer’s disease.

 

Read more at UNSW Science News