Ozren Bogdanovic

Laboratory Head, Garvan Institute of Medical Research
Senior Research Fellow

Ozren Bogdanovic is a Lab Head at the  Garvan Institute of Medical Research.  Ozren obtained his PhD from Radboud University (Nijmegen, the Netherlands), where he worked on DNA methylation and methyl CpG-binding proteins during early embryogenesis in the lab of Gert Jan Veenstra. Ozren then moved to the Andalusian Centre for Developmental Biology (CABD, Seville - Spain) to work with Jose Luis Gomez-Skarmeta and Juan Ramon Martinez-Morales on various aspects of embryonic gene regulation. There he led a number of developmental genetics projects and participated in the adaptation of next-generation sequencing technologies to vertebrate embryonic material. In 2013 Ozren started his postdoctoral studies at the University of Western Australia in the laboratory of Ryan Lister where he conducted research in the field of developmental and evolutionary epigenomics. His work at UWA includes the discovery of a highly conserved epigenome remodeling event associated with vertebrate body plan formation. Ozren joined the Garvan Institute of Medical Research as a Lab Head in February 2017. At the Garvan Ozren is applying integrative approaches to study the contribution of the epigenome to vertebrate embryogenesis and cancer formation.

Journal articles
add
Ross S; Angeloni A; de Mendoza A; Bogdanovic O, 2020, 'Pervasive non-CpG methylation at zebrafish mosaic satellite repeats', , http://dx.doi.org/10.1101/2020.05.13.093203
2020
Buono L; Naranjo S; Moreno-Marmol T; de la Cerda B; Polvillo R; Díaz-Corrales F-J; Bogdanovic O; Bovolenta P; Martínez-Morales J-R, 2020, 'Analysis of gene network bifurcation during optic cup morphogenesis in zebrafish', , http://dx.doi.org/10.1101/2020.05.28.121038
2020
de Mendoza A; Lister R; Bogdanovic O, 2020, 'Evolution of DNA Methylome Diversity in Eukaryotes', Journal of Molecular Biology, vol. 432, pp. 1687 - 1705, http://dx.doi.org/10.1016/j.jmb.2019.11.003
2020
Field MA; Rosen BD; Dudchenko O; Chan EKF; Minoche AE; Edwards RJ; Barton K; Lyons RJ; Tuipulotu DE; Hayes VM; Omer AD; Colaric Z; Keilwagen J; Skvortsova K; Bogdanovic O; Smith MA; Aiden EL; Smith TPL; Zammit RA; Ballard JWO, 2020, 'Canfam-GSD: De novo chromosome-length genome assembly of the German Shepherd Dog (Canis lupus familiaris) using a combination of long reads, optical mapping, and Hi-C', GigaScience, vol. 9, http://dx.doi.org/10.1093/gigascience/giaa027
2020
Skvortsova K; Masle-Farquhar E; Luu PL; Song JZ; Qu W; Zotenko E; Gould CM; Du Q; Peters TJ; Colino-Sanguino Y; Pidsley R; Nair SS; Khoury A; Smith GC; Miosge LA; Reed JH; Kench JG; Rubin MA; Horvath L; Bogdanovic O; Lim SM; Polo JM; Goodnow CC; Stirzaker C; Clark SJ, 2019, 'DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns', Cancer Cell, vol. 35, pp. 297 - 314.e8, http://dx.doi.org/10.1016/j.ccell.2019.01.004
2019
Angeloni A; Bogdanovic O, 2019, 'Enhancer DNA methylation: implications for gene regulation.', Essays Biochem, pp. EBC20190030 - EBC20190030, http://dx.doi.org/10.1042/EBC20190030
2019
Skvortsova K; Tarbashevich K; Stehling M; Lister R; Irimia M; Raz E; Bogdanovic O, 2019, 'Retention of paternal DNA methylome in the developing zebrafish germline', Nature Communications, vol. 10, http://dx.doi.org/10.1038/s41467-019-10895-6
2019
Ross SE; Bogdanovic O, 2019, 'TET enzymes, DNA demethylation and pluripotency', Biochemical Society Transactions, vol. 47, pp. 875 - 885, http://dx.doi.org/10.1042/BST20180606
2019
Marlétaz F; Firbas PN; Maeso I; Tena JJ; Bogdanovic O; Perry M; Wyatt CDR; de la Calle-Mustienes E; Bertrand S; Burguera D; Acemel RD; van Heeringen SJ; Naranjo S; Herrera-Ubeda C; Skvortsova K; Jimenez-Gancedo S; Aldea D; Marquez Y; Buono L; Kozmikova I; Permanyer J; Louis A; Albuixech-Crespo B; Le Petillon Y; Leon A; Subirana L; Balwierz PJ; Duckett PE; Farahani E; Aury JM; Mangenot S; Wincker P; Albalat R; Benito-Gutiérrez È; Cañestro C; Castro F; D’Aniello S; Ferrier DEK; Huang S; Laudet V; Marais GAB; Pontarotti P; Schubert M; Seitz H; Somorjai I; Takahashi T; Mirabeau O; Xu A; Yu JK; Carninci P; Martinez-Morales JR; Crollius HR; Kozmik Z; Weirauch MT; Garcia-Fernàndez J; Lister R; Lenhard B; Holland PWH; Escriva H; Gómez-Skarmeta JL; Irimia M, 2018, 'Amphioxus functional genomics and the origins of vertebrate gene regulation', Nature, vol. 564, pp. 64 - 70, http://dx.doi.org/10.1038/s41586-018-0734-6
2018
Skvortsova K; Iovino N; Bogdanović O, 2018, 'Functions and mechanisms of epigenetic inheritance in animals', Nature Reviews Molecular Cell Biology, vol. 19, pp. 774 - 790, http://dx.doi.org/10.1038/s41580-018-0074-2
2018
Bogdanović O; Lister R, 2017, 'DNA methylation and the preservation of cell identity', Current Opinion in Genetics and Development, vol. 46, pp. 9 - 14, http://dx.doi.org/10.1016/j.gde.2017.06.007
2017
Zenk F; Loeser E; Schiavo R; Kilpert F; Bogdanovic O; Iovino N, 2017, 'Germ line–inherited H3K27me3 restricts enhancer function during maternal-to-zygotic transition', Science, vol. 357, pp. 212 - 216, http://dx.doi.org/10.1126/science.aam5339
2017
Westhorpe F; Tiengwe C; Hunsberger H; Jain G; Wells M; Yu M; Bogdanovic O; Absalon S; Sen P; Madrigal P; Natarajan K, 2017, 'Postdocs, What Would You Tell Your Younger Self?', CELL, vol. 168, pp. 745 - 748, http://dx.doi.org/10.1016/j.cell.2017.02.016
2017
Crisp PA; Ganguly DR; Smith AB; Murray KD; Estavillo GM; Searle I; Ford E; Bogdanović O; Lister R; Borevitz JO; Eichten SR; Pogson BJ, 2017, 'Rapid recovery gene downregulation during excess-light stress and recovery in arabidopsis', Plant Cell, vol. 29, pp. 1836 - 1863, http://dx.doi.org/10.1105/tpc.16.00828
2017
Elurbe D; Paranjpe S; Georgiou G; van Kruijsbergen I; Bogdanovic O; Gibeaux R; Heald R; Lister R; Huynen M; van Heeringen S; Veenstra GJ, 2017, 'Regulatory remodeling in the allo-tetraploid frog Xenopus laevis', , http://dx.doi.org/10.1101/120212
2017
Ford E; Grimmer M; Stolzenburg S; Bogdanovic O; Mendoza AD; Farnham P; Blancafort P; Lister R, 2017, 'Frequent lack of repressive capacity of promoter DNA methylation identified through genome-wide epigenomic manipulation', , http://dx.doi.org/10.1101/170506
2017
Elurbe DM; Paranjpe SS; Georgiou G; van Kruijsbergen I; Bogdanovic O; Gibeaux R; Heald R; Lister R; Huynen MA; van Heeringen SJ; Veenstra GJC, 2017, 'Regulatory remodeling in the allo-tetraploid frog Xenopus laevis', Genome biology, vol. 18, pp. 198, http://dx.doi.org/10.1186/s13059-017-1335-7
2017
Hontelez S; van Kruijsbergen I; Georgiou G; van Heeringen SJ; Bogdanovic O; Lister R; Veenstra GJC, 2016, 'Embryonic transcription is controlled by maternally defined chromatin state (vol 6, 10148, 2015)', NATURE COMMUNICATIONS, vol. 7, http://dx.doi.org/10.1038/ncomms12208
2016
Bogdanović O; Van Heeringen SJ, 2016, 'ChiP-seq data processing for PcG proteins and associated Histone modifications', Methods in Molecular Biology, vol. 1480, pp. 37 - 53, http://dx.doi.org/10.1007/978-1-4939-6380-5_4
2016
Session AM; Uno Y; Kwon T; Chapman JA; Toyoda A; Takahashi S; Fukui A; Hikosaka A; Suzuki A; Kondo M; Van Heeringen SJ; Quigley I; Heinz S; Ogino H; Ochi H; Hellsten U; Lyons JB; Simakov O; Putnam N; Stites J; Kuroki Y; Tanaka T; Michiue T; Watanabe M; Bogdanovic O; Lister R; Georgiou G; Paranjpe SS; Van Kruijsbergen I; Shu S; Carlson J; Kinoshita T; Ohta Y; Mawaribuchi S; Jenkins J; Grimwood J; Schmutz J; Mitros T; Mozaffari SV; Suzuki Y; Haramoto Y; Yamamoto TS; Takagi C; Heald R; Miller K; Haudenschild C; Kitzman J; Nakayama T; Izutsu Y; Robert J; Fortriede J; Burns K; Lotay V; Karimi K; Yasuoka Y; Dichmann DS; Flajnik MF; Houston DW; Shendure J; Dupasquier L; Vize PD; Zorn AM; Ito M; Marcotte EM; Wallingford JB; Ito Y; Asashima M; Ueno N; Matsuda Y; Veenstra GJC; Fujiyama A; Harland RM; Taira M; Rokhsar DS, 2016, 'Genome evolution in the allotetraploid frog Xenopus laevis', Nature, vol. 538, pp. 336 - 343, http://dx.doi.org/10.1038/nature19840
2016
Bogdanović O; Smits AH; De La Calle Mustienes E; Tena JJ; Ford E; Williams R; Senanayake U; Schultz MD; Hontelez S; Van Kruijsbergen I; Rayon T; Gnerlich F; Carell T; Veenstra GJC; Manzanares M; Sauka-Spengler T; Ecker JR; Vermeulen M; Gómez-Skarmeta JL; Lister R, 2016, 'Active DNA demethylation at enhancers during the vertebrate phylotypic period', Nature Genetics, vol. 48, pp. 417 - 426, http://dx.doi.org/10.1038/ng.3522
2016
Bogdanović O; Veenstra GJC, 2011, 'Affinity-based enrichment strategies to assay methyl-CpG binding activity and DNA methylation in early Xenopus embryos.', BMC Res Notes, vol. 4, pp. 300, http://dx.doi.org/10.1186/1756-0500-4-300
2011

2017 - Millennium Science Award
2017 - Raine Research Prize
2016 - UWA Early Career Researcher Vice Chancellor’s Award
2016 - UWA Research Collaboration Award
2015 - UWA Research Collaboration Award
2014 - ECR Award to attend the annual meeting of the Australian Academy of Sciences
2014 - Cell Symposia – Transcriptional Regulation in Development, Poster Presentation Award 
2013 - ARC Discovery Early Career Researcher Award (DECRA)
2013 - EMBO travel grant
2003 - IAESTE internship to work at Friedrich Miescher Institute (Basel, CH)