Paul Waters

Associate Professor
Research Program

The lab focuses on better understanding the epigenetic regulation of transcription in diverse vertebrate representatives, specifically focussing on sex chromosomes. The ultimate goal is to understand how complex epigenetic silencing mechanisms evolved. We use eutherian, marsupial, monotreme and bird/reptile models. Representatives from these groups each have different (sometimes weird and wonderful) sex determining mechanisms and sex chromosome systems.

We examine X chromosome inactivation in wallabies and Tasmanian devils. We have particular interest in dosage compensation of the strange sex chromosomes of platypus, which have 5 X chromosomes and 5 Y chromosomes! We also study the Australian central bearded dragon, which are unusual in that they have both genetic and environmental sex determination. In more recent years we have been examining hibernation/brumation in dragon lizards.

Click here for a full list of publications. 

Some cover highlights (click to link out):

 

 Trends in Genetics cover Cell Reports cover MBE cover Nature genetics cover Nature cover Genome Research cover

 

Teaching

Coordinator:

  • 2ndyear Genetics (BABS2204/2264)

Lecturer:

  • Molecules, Cells and Genes(BABS1201)
  • Human Molecular Genetics and Disease(BABS3151)
  • Genes, Genomes and Evolution(BABS3291)
  • Beginnings, Growth and Development A (MFAC1521)
  • Beginnings, Growth and Development B (MFAC1522)

 

Supervision

PhD, MSc, Honours, and 3rd year Undergraduate projects in Epigenetics and Molecular Biology are available in the lab.

 

Professional Experience
  • 2019-current: Associate Professor, School of Biotechnology and Biomolecular Science
  • 2014-2019: Senior Lecturer, School of Biotechnology and Biomolecular Science
  • 2012-2014: ARC Fellow & Senior Lecturer, School of Biotechnology and Biomolecular Sciences
  • 2009-2012: ARC Fellow, Evolution Ecology & Genetics, Research School of Biology, ANU
  • 2007-2009: Research Fellow, Comparative Genomics Group, Research School of Biological Sciences, The Australian National University
  • 2006-2007: Postdoctoral Fellow, ARC Centre for Kangaroo Genomics, Comparative Genomics Group, Research School of Biological Science, ANU
  • 2003-2005: Postdoctoral Fellow, Evolutionary Genomics Group, Department of Zoology, Stellenbosch University, Private Bag X1, Matieland, South Africa

 

Funding
  • APP1182667NHMRC Ideas Grant. 2020-2023 (AUD $562k). Clemens K & Waters PD. A role for long non-coding RNA in the persistence of drug seeking.
  • DP180100931. ARC Discovery Project. 2018-2020 (AUD $432k). Waters PD & Morris KV.Silencing the X chromosome: Why and How.
  • DP170101147. ARC Discovery Project. 2017-2020 (AUD $1,007k). Georges A, Deakin AE, Sarre S, Ezaz T, Waters PD, Schwanz L, Graves JAM & Holleley C. Sex determination in dragons – genetics, epigenetics and environment. 
  • DP1094868ARC Discovery Project. 2010-2013 (AUD $315k). Waters PD, DeakinJE & Graves JA.Epigenetic silencing in vertebrates – evolution and function from the bottom-up. 
  • DP0987091Australian Research Fellowship. 2009-2014 (AUD $560k). Waters PD. Origin and Evolution of Mammalian Dosage Compensation.

 

Conference Papers
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Eyck HJF; Sarma RR; Crino OL; Waters PD; Crossland M; Shine R; Rollins LA, 2020, 'Corticosterone response to experimental manipulation of methylation in invasive amphibian larvae', in INTEGRATIVE AND COMPARATIVE BIOLOGY, OXFORD UNIV PRESS INC, Austin, TX, pp. E66 - E66, presented at Annual Meeting of the Society-for-Integrative-and-Comparative-Biology (SICB), Austin, TX, 03 January 2020 - 07 January 2020, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000536432400263&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2020
Veyrunes F; Rens W; Waters P; Miethke P; Alsop A; Grutzner F; Deakin J; Ferguson-Smith M; Graves J, 2007, 'Does the platypus sex chromosome system derive from an ancestral bird ZW system?', in CHROMOSOME RESEARCH, SPRINGER, Amsterdam, NETHERLANDS, pp. 72 - 73, presented at 16th International Chromosome Conference (ICC 16), Amsterdam, NETHERLANDS, 25 August 2007 - 29 August 2007, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000249018100177&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2007
Robinson T; Waters P; Ruiz-Herrera A; Dobigny G; Garcia M, 2007, 'Sex chromosomes of basal placental mammals', in CHROMOSOME RESEARCH, SPRINGER, Amsterdam, NETHERLANDS, pp. 75 - 75, presented at 16th International Chromosome Conference (ICC 16), Amsterdam, NETHERLANDS, 25 August 2007 - 29 August 2007, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000249018100183&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2007
Graves JAM; Waters PD, 2001, 'Mammalian sex chromosome evolution - The rise and fall of the Y chromosome', in Schmid M (ed.), CHROMOSOMES TODAY, VOL 14, SPRINGER, Wurzburg, GERMANY, pp. 3 - 14, presented at 14th International Chromosomes Conference, Wurzburg, GERMANY, 04 September 2001 - 08 September 2001, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000221466300001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2001
Journal articles
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Waters PD; Ruiz-Herrera A, 2020, 'Meiotic Executioner Genes Protect the Y from Extinction', Trends in Genetics, http://dx.doi.org/10.1016/j.tig.2020.06.008
2020
Sarma RR; Edwards RJ; Crino OL; Eyck HJF; Waters PD; Crossland MR; Shine R; Rollins LA, 2020, 'Do epigenetic changes drive corticosterone responses to alarm cues in larvae of an invasive amphibian?', Integr Comp Biol, http://dx.doi.org/10.1093/icb/icaa082
2020
Vara C; Paytuví-Gallart A; Cuartero Y; Le Dily F; Garcia F; Salvà-Castro J; Gómez-H L; Julià E; Moutinho C; Aiese Cigliano R; Sanseverino W; Fornas O; Pendás AM; Heyn H; Waters PD; Marti-Renom MA; Ruiz-Herrera A, 2019, 'Three-Dimensional Genomic Structure and Cohesin Occupancy Correlate with Transcriptional Activity during Spermatogenesis', Cell Reports, vol. 28, pp. 352 - 367.e9, http://dx.doi.org/10.1016/j.celrep.2019.06.037
2019
Waters S; Waters P; Capraro A, 2019, 'Waking the sleeping dragon: gene expression profiling reveals adaptive strategies of the hibernating reptile Pogona vitticeps', BMC Genomics, http://dx.doi.org/10.1186/s12864-019-5750-x
2019
Sprague D; Waters SA; Kirk JM; Wang JR; Samollow PB; Waters PD; Calabrese JM, 2019, 'Nonlinear sequence similarity between the Xist and Rsx long noncoding RNAs suggests shared functions of tandem repeat domains', RNA, vol. 25, pp. 1004 - 1019, http://dx.doi.org/10.1261/rna.069815.118
2019
Waters SA; Livernois AM; Patel H; O’Meally D; Craig JM; Marshall Graves JA; Suter CM; Waters PD, 2018, 'Landscape of DNA methylation on the marsupial x', Molecular Biology and Evolution, vol. 35, pp. 431 - 439, http://dx.doi.org/10.1093/molbev/msx297
2018
Johnson RN; O’Meally D; Chen Z; Etherington GJ; Ho SYW; Nash WJ; Grueber CE; Cheng Y; Whittington CM; Dennison S; Peel E; Haerty W; O’Neill RJ; Colgan D; Russell TL; Alquezar-Planas DE; Attenbrow V; Bragg JG; Brandies PA; Chong AYY; Deakin JE; Di Palma F; Duda Z; Eldridge MDB; Ewart KM; Hogg CJ; Frankham GJ; Georges A; Gillett AK; Govendir M; Greenwood AD; Hayakawa T; Helgen KM; Hobbs M; Holleley CE; Heider TN; Jones EA; King A; Madden D; Graves JAM; Morris KM; Neaves LE; Patel HR; Polkinghorne A; Renfree MB; Robin C; Salinas R; Tsangaras K; Waters PD; Waters SA; Wright B; Wilkins MR; Timms P; Belov K, 2018, 'Adaptation and conservation insights from the koala genome', Nature Genetics, vol. 50, pp. 1102 - 1111, http://dx.doi.org/10.1038/s41588-018-0153-5
2018
Waters SA; Capraro A; McIntyre KL; Graves JAM; Waters PD, 2018, 'The methylome of vertebrate sex chromosomes', Genes, vol. 9, http://dx.doi.org/10.3390/genes9050230
2018
Waters PD, 2017, 'Fragile Y Chromosomes (retrospective on DOI 10.1002/bies.201500040)', BioEssays, vol. 39, http://dx.doi.org/10.1002/bies.201700142
2017
Deveson IW; Holleley CE; Blackburn J; Marshall Graves JA; Mattick JS; Waters PD; Georges A, 2017, 'Differential intron retention in Jumonji chromatin modifier genes is implicated in reptile temperature-dependent sex determination', Science Advances, vol. 3, http://dx.doi.org/10.1126/sciadv.1700731
2017
Waters PD, 2015, 'The loss of fragile Y chromosomes (comment on 10.1002/bies.201500040)', BioEssays, vol. 37, pp. 933 - 933, http://dx.doi.org/10.1002/bies.201500091
2015
Waters SA; Waters PD, 2015, 'Imprinted X chromosome inactivation: evolution of mechanisms in distantly related mammals', AIMS GENETICS, vol. 2, pp. 110 - 126, http://dx.doi.org/10.3934/genet.2015.2.110
2015
Munroe SH; Morales CH; Duyck TH; Waters PD, 2015, 'Evolution of the antisense overlap between genes for thyroid hormone receptor and rev-erbα and characterization of an exonic G-rich element that regulates splicing of TRα2 mRNA', PLoS ONE, vol. 10, http://dx.doi.org/10.1371/journal.pone.0137893
2015
Georges A; Li Q; Lian J; O'Meally D; Deakin J; Wang Z; Zhang P; Fujita M; Patel HR; Holleley CE; Zhou Y; Zhang X; Matsubara K; Waters P; Graves JAM; Sarre SD; Zhang G, 2015, 'High-coverage sequencing and annotated assembly of the genome of the Australian dragon lizard Pogona vitticeps', GigaScience, vol. 4, http://dx.doi.org/10.1186/s13742-015-0085-2
2015
Mills JD; Kavanagh T; Kim WS; Chen BJ; Waters PD; Halliday GM; Janitz M, 2015, 'High expression of long intervening non-coding RNA OLMALINC in the human cortical white matter is associated with regulation of oligodendrocyte maturation', Molecular brain, vol. 8, pp. 2, http://dx.doi.org/10.1186/s13041-014-0091-9
2015
Mills JD; Chen J; Kim WS; Waters PD; Prabowo AS; Aronica E; Halliday GM; Janitz M, 2015, 'Long intervening non-coding RNA 00320 is human brain-specific and highly expressed in the cortical white matter', Neurogenetics, vol. 16, pp. 201 - 213, http://dx.doi.org/10.1007/s10048-015-0445-1
2015
Rodríguez-Delgado CL; Waters SA; Waters DP, 2014, 'Paternal X inactivation does not correlate with X chromosome evolutionary strata in marsupials', BMC Evolutionary Biology, vol. 14, http://dx.doi.org/10.1186/s12862-014-0267-z
2014
Cortez D; Marin R; Toledo-Flores D; Froidevaux L; Liechti A; Waters PD; Grützner F; Kaessmann H, 2014, 'Origins and functional evolution of y chromosomes across mammals', Nature, vol. 508, pp. 488 - 493, http://dx.doi.org/10.1038/nature13151
2014
Gilbert C; Waters P; Feschotte C; Schaack S, 2013, 'Horizontal transfer of OC1 transposons in the Tasmanian devil', BMC Genomics, vol. 14, http://dx.doi.org/10.1186/1471-2164-14-134
2013
Li G; Davis BW; Raudsepp T; Wilkerson AJP; Mason VC; Ferguson-Smith M; O'Brien PC; Waters PD; Murphy WJ, 2013, 'Comparative analysis of mammalian y chromosomes illuminates ancestral structure and lineage-specific evolution', Genome Research, vol. 23, pp. 1486 - 1495, http://dx.doi.org/10.1101/gr.154286.112
2013
Livernois AM; Waters SA; Deakin JE; Marshall Graves JA; Waters PD, 2013, 'Independent Evolution of Transcriptional Inactivation on Sex Chromosomes in Birds and Mammals', PLoS Genetics, vol. 9, http://dx.doi.org/10.1371/journal.pgen.1003635
2013
Livernois AM; Graves JAM; Waters PD, 2012, 'The origin and evolution of vertebrate sex chromosomes and dosage compensation', Heredity, vol. 108, pp. 50 - 58, http://dx.doi.org/10.1038/hdy.2011.106
2012
Chaumeil J; Waters PD; Koina E; Gilbert C; Robinson TJ; Graves JAM, 2011, 'Evolution from XIST-independent to XIST-controlled X-chromosome inactivation: Epigenetic modifications in distantly related mammals', PLoS ONE, vol. 6, pp. e19040, http://dx.doi.org/10.1371/journal.pone.0019040
2011
Murtagh V; O''Meally D; Sankovic N; Delbridge ML; Kuroki Y; Boore JL; Toyoda A; Jordan KS; Pask AJ; Renfree MB; Fujiyama A; Graves JA; Waters PD, 2011, 'Evolutionary history of novel genes on the tammar wallaby Y chromosome: Implications for sex chromosome evolution', Genome Research, vol. 22, pp. 498 - 507, http://dx.doi.org/10.1101/gr.120790.111
2011
Renfree MB; Papenfuss AT; Deakin JE; Lindsay J; Heider T; Belov K; Rens W; Waters PD; Pharo EA; Shaw G; Wong ESW; Lefèvre CM; Nicholas KR; Kuroki Y; Wakefield MJ; Zenger KR; Wang C; Ferguson-Smith M; Nicholas FW; Hickford D; Yu H; Short KR; Siddle HV; Frankenberg SR; Chew KY; Menzies BR; Stringer JM; Suzuki S; Hore TA; Delbridge ML; Mohammadi A; Schneider NY; Hu Y; O'Hara W; Al Nadaf S; Wu C; Feng ZP; Cocks BG; Wang J; Flicek P; Searle SMJ; Fairley S; Beal K; Herrero J; Carone DM; Suzuki Y; Sugano S; Toyoda A; Sakaki Y; Kondo S; Nishida Y; Tatsumoto S; Mandiou I; Hsu A; McColl KA; Lansdell B; Weinstock G; Kuczek E; McGrath A; Wilson P; Men A; Hazar-Rethinam M; Hall A; Davis J; Wood D; Williams S; Sundaravadanam Y; Muzny DM; Jhangiani SN; Lewis LR; Morgan MB; Okwuonu GO; Ruiz SJ; Santibanez J; Nazareth L; Cree A; Fowler G; Kovar CL; Dinh HH; Joshi V; Jing C; Lara F; Thornton R; Chen L; Deng J; Liu Y; Shen JY; Song XZ; Edson J; Troon C; Thomas D; Stephens A; Yapa L; Levchenko T; Gibbs RA; Cooper DW; Speed TP; Fujiyama A; M Graves JA; O'Neill RJ, 2011, 'Genome sequence of an Australian kangaroo, Macropus eugenii, provides insight into the evolution of mammalian reproduction and development', Genome Biology, vol. 12, http://dx.doi.org/10.1186/gb-2011-12-8-r81
2011
Badenhorst D; Dobigny G; Adega F; Chaves R; O''Brien PCM; Ferguson-smith MA; Waters PD; Robinson TJ, 2011, 'Chromosomal evolution in Rattini (Muridae,Rodentia)', Chromosome Research, vol. 19, pp. 709 - 727, http://dx.doi.org/10.1007/s10577-011-9227-2
2011
Al Nadaf S; Deakin JE; Gilbert C; Robinson TJ; Graves JA; Waters PD, 2011, 'A cross-species comparison of escape from X inactivation in Eutheria: implications for evolution of X chromosome inactivation.', Chromosoma, vol. 121, pp. 71 - 78, http://dx.doi.org/10.1007/s00412-011-0343-8
2011
Al Nadaf S; Waters PD; Koina E; Deakin JE; Jordan KS; Graves JAM, 2010, 'Activity map of the tammar X chromosome shows that marsupial X inactivation is incomplete and escape is stochastic', Genome Biology, vol. 11, http://dx.doi.org/10.1186/gb-2010-11-12-r122
2010
Delgado CL; Waters PD; Gilbert C; Robinson TJ; Graves JA, 2009, 'Physical mapping of the elephant X chromosome: conservation of gene order over 105 million years.', Chromosome Research, vol. 17, pp. 917 - 926, http://dx.doi.org/10.1007/s10577-009-9079-1
2009
Waters PD; Graves JA, 2009, 'Monotreme sex chromosomes – implications for the evolution of amniote sex chromosomes', Reproduction Fertility and Development, vol. 21, pp. 943 - 951, http://dx.doi.org/10.1071/RD09250
2009
Mohammadi A; Delbridge ML; Waters PD; Graves JA, 2009, 'Conservation of a chromosome arm in two distantly related marsupial species.', Cytogenetic and Genome Research, vol. 124, pp. 147 - 150, http://dx.doi.org/10.1159/000207522
2009
Ezaz T; Moritz B; Waters PD; Graves JA; Georges A; Sarre SD, 2009, 'The ZW sex microchromosomes of an Australian dragon lizard share no homology with those of other reptiles or birds', Chromosome Research, vol. 17, pp. 965 - 973, http://dx.doi.org/10.1007/s10577-009-9102-6
2009
Delbridge ML; Patel HR; Waters PD; Mcmillan DA; Graves JA, 2009, 'Does the human X contain a third evolutionary block? Origin of genes on human Xp11 and Xq28.', Genome Research, vol. 19, pp. 1350 - 1360, http://dx.doi.org/10.1101/gr.088625.108
2009
Deakin J; Koina E; Waters PD; Doherty R; Patel VS; Delbridge ML; Dobson B; Fong J; Hu Y; Hurk C; Pask AJ; Shaw G; Smith C; Thompson K; Wakefield MJ; Yu H; Renfree M; Graves JA, 2008, 'Physical map of two tammar wallaby chromosomes: a strategy for mapping in non-model mammals', Chromosome Research, vol. 16, pp. 1159 - 1175, http://dx.doi.org/10.1007/s10577-008-1266-y
2008
Wallis MC; Waters PD; Graves JA, 2008, 'Sex determination in mammals-before and after the evolution of SRY', CMLS - Cellular and Molecular Life Sciences, vol. 65, pp. 3182 - 3195, http://dx.doi.org/10.1007/s00018-008-8109-z
2008
Veyrunes F; Waters PD; Miethke P; Rens W; McMillan D; Alsop AE; Grutzner F; Deakin J; Whittington CM; Schatzkamer K; Kremitzki CL; Graves T; Ferguson-smith MA; Warren W; Marshall Graves JA, 2008, 'Bird-like sex chromosomes of platypus imply recent origin of mammal sex chromosomes.', Genome Research, vol. 18, pp. 965 - 973, http://dx.doi.org/10.1101/gr.7101908
2008
Gilbert C; Pace JK; Waters PD, 2008, 'Target site analysis of RTE1_LA and its AfroSINE partner in the elephant genome', Gene, vol. 425, pp. 1 - 8, http://dx.doi.org/10.1016/j.gene.2008.08.013
2008
Waters PD; Dobigny G; Waddell PJ; Robinson TJ, 2008, 'LINE-1 elements: analysis by fluorescence in-situ hybridization and nucleotide sequences.', Methods in molecular biology (Clifton, N.J.), vol. 422, pp. 227 - 237
2008
Warren WC; Hillier LW; Graves JAM; Birney E; Ponting CP; Grutzner F; Belov K; Miller W; Clarke L; Chinwalla AT; Yang SP; Heger A; Locke D; Miethke P; Waters PD; Veyrunes F; Fulton L; Fulton B; Graves T; Wallis J; Puente XS; Lopez-Otin C; Ordonez C; Eichler EE; Chen L; Cheng Z; Deakin J; Alsop A; Thompson K; Kirby P; Papenfuss AT; Wakefield MJ; Olender T; Lancet D; Huttley GA; Smit AFA; Pask A; Temple-Smith P; Batzer MA; Walker JA; Konkel MK; Harris RS; Whittington CM; Wong ESW; Gemmell NJ; Buschiazzo E; Vargas Jentzsch IM; Merkel A; Schmitz J; Zemann A; Churakov G; Kriegs JO; Brosius J; Murchison EP; Sachidanandam R; Smith C; Hannon GJ; Tsend-Ayush E; McMillan D; Attenborough R; Rens W; Ferguson-Smith M; Lefevre CM; Sharp JA; Nicholas KR; Ray DA; Kube M; Reinhardt R; Pringle TH; Taylor J; Jones RC; Nixon B; Dacheux JL; Niwa H; Sekita Y; Huang X; Stark A; Kheradpour P; Kellis M; Flicek P; Chen Y; Webber C; Hardison R; Nelson J; Hallsworth-Pepin K; Delehaunty K; Markovic C; Minx P; Feng Y; Kremitzki C; Mitreva M; Glasscock J; Wylie T; Wohldmann P; Thiru P; Nhan MN; Pohl CS; Smith SM; Hou S; Renfree M; Mardis ER; Wilson RK, 2008, 'Genome analysis of the platypus reveals unique signatures of evolution', Nature, vol. 453, pp. 175 - 184, http://dx.doi.org/10.1038/nature06936
2008
Deuve JL; Bennett NC; Ruiz-Herrera A; Waters PD; Britton-Davidian J; Robinson TJ, 2008, 'Dissection of a Y-autosome translocation in Cryptomys hottentotus (Rodentia, Bathyergidae) and implications for the evolution of a meiotic sex chromosome chain', Chromosoma, vol. 177, pp. 211 - 217, http://dx.doi.org/10.1007/s00412-007-0140-6
2008
Gilbert C; Pace JK; Waters PD, 2008, 'Target site analysis of RTE1_LA and its AfroSINE partner in the elephant genome', Gene, vol. 425, pp. 1 - 8
2008
Warren WC; Hillier LDW; Marshall Graves JA; Birney E; Ponting CP; Grützner F; Belov K; Miller W; Clarke L; Chinwalla AT; Yang SP; Heger A; Locke DP; Miethke P; Waters PD; Veyrunes F; Fulton L; Fulton B; Graves T; Wallis J; Puente XS; López-Otín C; Ordó̃ez GR; Eichler EE; Chen L; Cheng Z; Deakin JE; Alsop A; Thompson K; Kirby P; Papenfuss AT; Wakefield MJ; Olender T; Lancet D; Huttley GA; Smit AFA; Pask A; Temple-Smith P; Batzer MA; Walker JA; Konkel MK; Harris RS; Whittington CM; Wong ESW; Gemmell NJ; Buschiazzo E; Vargas Jentzsch IM; Merkel A; Schmitz J; Zemann A; Churakov G; Kriegs JO; Brosius J; Murchison EP; Sachidanandam R; Smith C; Hannon GJ; Tsend-Ayush E; McMillan D; Attenborough R; Rens W; Ferguson-Smith M; Lefèvre CM; Sharp JA; Nicholas KR; Ray DA; Kube M; Reinhardt R; Pringle TH; Taylor J; Jones RC; Nixon B; Dacheux JL; Niwa H; Sekita Y; Huang X; Stark A; Kheradpour P; Kellis M; Flicek P; Chen Y; Webber C; Hardison R; Nelson J; Hallsworth-Pepin K; Delehaunty K; Markovic C; Minx P; Feng Y; Kremitzki C; Mitreva M; Glasscock J; Wylie T; Wohldmann P; Thiru P; Nhan MN; Pohl CS; Smith SM; Hou S; Nefedov M, 2008, 'Genome analysis of the platypus reveals unique signatures of evolution (Nature (2008) 453, (175-183))', Nature, vol. 455, pp. 256, http://dx.doi.org/10.1038/nature07253
2008
Waters PD; Marshall Graves JA; Thompson K; Sankovic N; Ezaz T, 2008, 'Identification of cryptic sex chromosomes and isolation of X- and Y-borne genes.', Methods in molecular biology (Clifton, N.J.), vol. 422, pp. 239 - 251, http://dx.doi.org/10.1007/978-1-59745-581-7_15
2008
Wallis MC; Waters PD; Delbridge ML; Kirby PJ; Pask A; Grutzner F; Rens W; Ferguson-smith MA; Graves JA, 2007, 'Sex determination in platypus and echidna: autosomal location of SOX3 confirms the absence of SRY from monotremes.', Chromosome Research, vol. 15, pp. 949 - 959, http://dx.doi.org/10.1007/s10577-007-1185-3
2007
Waters PD; Wallis MC; Marshall Graves JA, 2007, 'Mammalian sex – origin and evolution of the Y chromosome and SRY', Seminars in Cell and Developmental Biology, vol. 18, pp. 389 - 400, http://dx.doi.org/10.1016/j.semcdb.2007.02.007
2007
Waters PD; Ruiz-Herrera A; Dobigny G; Garcia Caldes M; Robinson TJ, 2007, 'Sex chromosomes of basal placental mammals', Chromosoma, vol. 116, pp. 511 - 518, http://dx.doi.org/10.1007/s00412-007-0116-6
2007
Mikkelsen TS; Wakefield MJ; Aken B; Amemiya CT; Chang JL; Duke S; Garber M; Gentles AJ; Goodstadt L; Heger A; Jurka J; Kamal M; Mauceli E; Searle SM; Sharpe T; Baker ML; Batzer MA; Benos PV; Belov K; Clamp M; Cook A; Cuff J; Das R; Davidow L; Deakin J; Fazzari MJ; Glass JL; Grabherr M; Greally JM; Gu W; Hore TA; Huttley GA; Kleber M; Jirtle RL; Koina E; Lee JT; Mahony S; Marra MA; Miller RD; Nicholls RD; Oda M; Papenfuss AT; Parra ZE; Pollock DD; Ray DA; Schein JE; Speed TP; Thompson K; Vandeberg JL; Wade CM; Walker JA; Waters PD; Webber C; Weidman JR; Xie X; Zody MC; Graves JA; Ponting CP; Breen M; Samollow PB; Lander ES; Lindblad-Toh K, 2007, 'Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences.', Nature, vol. 447, pp. 167 - 177, http://dx.doi.org/10.1038/nature05805
2007
Kirby PJ; Greaves IK; Koina E; Waters PD; Marshall Graves JA, 2007, 'CORE-SINE blocks comprise a large fraction of monotreme genomes; implications for vertebrate chromosome evolution.', Chromosome Research, vol. 15, pp. 975 - 984, http://dx.doi.org/10.1007/s10577-007-1187-1
2007
Waters PD; Dobigny G; Waddell PJ; Robinson TJ, 2007, 'Evolutionary history of LINE-1 in the major clades of placental mammals', PLoS ONE, vol. 2, pp. e158, http://dx.doi.org/10.1371/journal.pone.0000158
2007
Dobigny G; Waters PD; Robinson TJ, 2006, 'Absence of hypomethylation and LINE-1 amplification in a white x black rhinoceros hybrid', Genetica, vol. 127, pp. 81 - 86, http://dx.doi.org/10.1007/s10709-005-2483-3
2006
Waters PD; Delbridge ML; Deakin JE; El-Mogharbel N; Kirby PJ; Carvalho-Silva DR; Marshall Graves JA, 2005, 'Autosomal location of genes from the conserved mammalian X in the platypus (Ornithorhynchus anatinus): Implications for mammalian sex chromosome evolution', Chromosome Research, vol. 13, pp. 401 - 410, http://dx.doi.org/10.1007/s10577-005-0978-5
2005
Carvalho-Silva DR; O'Neill RJW; Brown JD; Huynh K; Waters PD; Pask AJ; Delbridge ML; Marshall Graves JA, 2004, 'Molecular characterization and evolution of X and Y-borne ATRX homologues in American marsupials', Chromosome Research, vol. 12, pp. 795 - 804, http://dx.doi.org/10.1007/s10577-005-5376-5
2004
Waters PD; Dobigny G; Pardini AT; Robinson TJ, 2004, 'LINE-1 distribution in Afrotheria and Xenarthra: Implications for understanding the evolution of LINE-1 in eutherian genomes', Chromosoma, vol. 113, pp. 137 - 144, http://dx.doi.org/10.1007/s00412-004-0301-9
2004
Dobigny G; Ozouf-Costaz C; Waters PD; Bonillo C; Coutanceau JP; Volobouev V, 2004, 'LINE-1 amplification accompanies explosive genome repatterning in rodents', Chromosome Research, vol. 12, pp. 787 - 793, http://dx.doi.org/10.1007/s10577-005-5265-y
2004
Waters PD; Sankovic N; Kirby PJ; Delbridge ML; Graves JA, 2003, 'Assignment of the thymosin beta 4 X/Y chromosome (TMSB4X/Y) gene to tammar wallaby chromosome 5p by fluorescence in situ hybridisation', Cytogenetic and Genome Research, vol. 103, http://dx.doi.org/10.1159/000076317
2003
Kirby PJ; Waters PD; Delbridge M; Svartman M; Stewart AN; Nagai K; Graves JAM, 2002, 'Cloning and mapping of platypus SOX2 and SOX14: Insights into SOX group B evolution', Cytogenetic and Genome Research, vol. 98, pp. 96 - 100, http://dx.doi.org/10.1159/000068539
2002
Waters PD; Kirby PJ; Graves JAM, 2002, 'Assignment of the protocadherin 20 (PCDH20) gene to tammar wallaby chromosome 6q by fluorescence in situ hybridisation', Cytogenetic and Genome Research, vol. 98, http://dx.doi.org/10.1159/000071058
2002
Waters PD; Kirby PJ; Graves JAM, 2001, 'Assignment1 of the SMARCF1 gene to tammar wallaby chromosome 5q by fluorescence in situ hybridisation', Cytogenetics and Cell Genetics, vol. 93, pp. 315 - 316
2001
Waters PD; Duffy B; Frost CJ; Delbridge ML; Graves JAM, 2001, 'The human Y chromosome derives largely from a single autosomal region added to the sex chromosomes 80-130 million years ago', Cytogenetics and Cell Genetics, vol. 92, pp. 74 - 79, http://dx.doi.org/10.1159/000056872
2001
Working Papers
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Youngson N; Castino M; Stuart A; Kershaw K; Holmes N; Waters P; Morris K; Clemens K, 2019, A natural antisense to brain-derived neurotrophic factor impairs extinction of drug seeking, http://dx.doi.org10.1101/851949
2019
Book Chapters
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McIntyre K; Waters S; Waters P, 2018, 'Sex Chromosomes', in Skinner MK (ed.), Encyclopedia of Reproduction, edn. 2, Academic Press, pp. 238 - 244, http://dx.doi.org/10.1016/B978-0-12-801238-3.64459-8
2018
Al Nadaf S; Waters PD; Deakin JE; Graves JAM, 2010, 'Marsupial genetics reveals insights into evolution of mammalian X chromosome inactivation', in Marsupial Genetics and Genomics, pp. 259 - 280, http://dx.doi.org/10.1007/978-90-481-9023-2_13
2010
Murtagh VJ; Waters PD; Marshall Graves JA, 2010, 'Compact but complex - The marsupial Y chromosome', in Marsupial Genetics and Genomics, pp. 207 - 228, http://dx.doi.org/10.1007/978-90-481-9023-2_11
2010
Books
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Waters PD; Deakin JE, 2010, Part VIII: Marsupial genes and gene evolution, http://dx.doi.org/10.1007/978-90-481-9023-2
2010
Waters PD, 2010, Part IV: Marsupial sex chromosomes, http://dx.doi.org/10.1007/978-90-481-9023-2
2010
Deakin JE; Waters PD; Graves JAM, 2010, Preface, http://dx.doi.org/10.1007/978-90-481-9023-2
2010
Waters PD, 2010, Part V: Marsupial epigenetics, http://dx.doi.org/10.1007/978-90-481-9023-2
2010
Deakin JE; Waters PD; Graves JAM, 2010, Marsupial genetics and genomics, http://dx.doi.org/10.1007/978-90-481-9023-2
2010

My central area of expertise is sex chromosome biology, with a focus on epigenetic regulation of the X chromosome. In more recent years, I have also worked on hibernation in bearded dragons.