Peter Philip Gray

Emeritus Professor

PUBLICATIONS

Journal articles
add
Lee LK; Bryant KJ; Bouveret R; Lei P; Duff AP; Harrop SJ; Huang EP; Gelb M; Gray PP; Curmi PM; Cunningham AM; Church WB; Scott KF; Harvey R, 2013, 'Selective inhibition of human group IIA-secreted phospholipase a 2 (hGIIA) signaling reveals arachidonic acid metabolism is associated with colocalization of hGIIA to vimentin in rheumatoid synoviocytes', The Journal of Biological Chemistry, vol. 288, pp. 15269 - 15279, http://dx.doi.org/10.1074/jbc.M112.397893
2013
Sleiman RJ; Gray PP; McCall M; Codamo J; Sunstrom N, 2008, 'Accelerated cell line development using two-color fluorescence activated cell sorting to select highly expressing antibody-producing clones', Biotechnology and Bioengineering, vol. 99, pp. 578 - 587, http://dx.doi.org/10.1002/bit.21612
2008
Huang EP; Marquis C; Gray PP, 2007, 'Development of Super-CHO protein-free medium based on a statistical design', Journal of Chemical Technology and Biotechnology, vol. 82, pp. 431 - 441, http://dx.doi.org/10.1002/jctb.1670
2007
Prowse AB; Mcquade LR; Bryant KJ; Marcal H; Gray PP, 2007, 'Identification of potential pluripotency determinants for human embryonic stem cells following proteomic analysis of human and mouse fibroblast conditioned media', Journal of Proteome Research, vol. 6, pp. 3796 - 3807, http://dx.doi.org/10.1021/pr0702262
2007
Catzel D; Chin DY; Stanton P; Gray PP; Mahler SM, 2006, 'Fractionation of follicle stimulating hormone charge isoforms in their native form by preparative electrophoresis technology', Journal of Biotechnology, vol. 122, pp. 73 - 85, http://dx.doi.org/10.1016/j.jbiotec.2005.08.026
2006
Mahler SM; Leong S; Gilbert A; Yan F; Gray PP; Van Dyk DD; Roeth P, 2006, 'Purification of monoclonal antibodies from cell culture supernatants by Gradiflow [trademark] electrophoresis technology', Journal of Chemical Technology and Biotechnology, vol. 81, pp. 445 - 453, http://dx.doi.org/10.1002/jctb.1426
2006
Prowse AB; Mcquade LR; Bryant KJ; Van Dyk DD; Tuch BE; Gray PP, 2005, 'A proteome analysis of conditioned media from human neonatal fibroblasts used in the maintenance of human embryonic stem cells', Proteomics, vol. 5, pp. 978 - 989, http://dx.doi.org/10.1002/pmic.200401087
2005
Huang EP; Marquis C; Gray PP, 2004, 'Process development for a recombinant Chinese hamster ovary (CHO) cell line utilizing a metal induced and amplified metallothionein expression system', Biotechnology and Bioengineering, vol. 88, pp. 437 - 450, http://dx.doi.org/10.1002/bit.20194
2004
De Boer L; Gray PP; Sunstrom N, 2004, 'Enhanced productivity of G1 phase Chinese hamster ovary cells using theGADD153 promoter', Biotechnology Letters, vol. 26, pp. 61 - 65, http://dx.doi.org/10.1023/B:BILE.0000009462.10772.a4
2004
Van Dyk DD; Misztal DD; Wilkins MR; Poljak A; Mackintosh JA; Varnai JC; Teber E; Walsh B; Gray PP, 2003, 'Identification of cellular changes associated with increased production of human growth hormone in a recombinant Chinese hamster ovary cell line.', Proteomics, vol. 3, pp. 147 - 156, http://dx.doi.org/10.1002/pmic.200390023
2003
Keane J; Ryan D; Gray PP, 2003, 'Effect of Shear Stress on Expression of a Recombinant Protein by Chinese Hamster Ovary Cells', Biotechnology and Bioengineering, vol. 81, pp. 211 - 220, http://dx.doi.org/10.1002/bit.10472
2003
Lalevski H; Marquis C; Catzel D; Gray PP; Van Dyk DD; Mahler SM, 2003, 'Purification of recombinant human growth hormone from CHO cell culture supernatant by Gradiflow preparative electrophoresis technology', Protein Expression and Purification, vol. 32, pp. 126 - 134, http://dx.doi.org/10.1016/j.pep.2003.07.002
2003
Sunstrom N; Gay RD; Wong CD; Kitchen NA; De Boer L; Gray PP, 2000, 'Insulin-like growth factor-I and transferrin mediate growth and survival of Chinese hamster ovary cells', Biotechnology Progress, vol. 16, pp. 698 - 702, http://dx.doi.org/10.1021/bp000102t
2000
Sunstrom N; Sugiyono ; Hunt SM; Bailey CG; Baig M; Sleigh MJ; Gray PP, 2000, 'Regulated autocrine growth of CHO cells', Cytotechnology, vol. 34, pp. 39 - 46
2000
Ward RL; Packham D; Smythe AM; Anderson-Stewart P; Kitchen NA; Phillips P; Gray PP; Prabakaran K; Freund J; Fullham M; Rule M; Dalley D; Meagher AP; Hawkins NJ; Smith G, 2000, 'Phase I clinical trial of the chimeric monoclonal antibody (c30.6) in patients with metastatic colorectal cancer', Clinical Cancer Research, vol. 6, pp. 4674 - 4683, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000166160200013&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2000
Bailey CG; Baig M; Gray PP; Sunstrom N, 1999, 'A rapid selection/amplification procedure for high-level expression of recombinant protein in a metal-amplifiable mammalian expression system', Biotechnology Techniques, vol. 13, pp. 615 - 619, http://dx.doi.org/10.1023/A:1008926708028
1999
Sunstrom N; Baig M; Cheng L; Payet DL; Sugiyono ; Gray PP, 1998, 'Recombinant insulin-like growth factor-I (IGF-I) production in Super-CHO results in the expression of IGF-I receptor and IGF binding protein 3', Cytotechnology, vol. 28, pp. 91 - 99, http://dx.doi.org/10.1023/A:1008073513948
1998
Hunt SM; Pak SC; Bridges MW; Gray PP; Sleigh MJ, 1997, 'CHINESE HAMSTER OVARY CELLS PRODUCE SUFFICIENT RECOMBINANT INSULIN-LIKE GROWTH FACTOR I TO SUPPORT GROWTH IN SERUM-FREE MEDIUM.', Cytotechnology, vol. 24, pp. 55 - 64, http://dx.doi.org/10.1023/A:1007969502256
1997
Chin CK; Schofield PR; Robertson DM; Gray PP; Chotigeat W; Mahler SM, 1996, 'Biological activity and metabolic clearance of recombinant human follicle stimulating hormone produced in Sp2/0 myeloma cells', Cytotechnology, vol. 21, pp. 171 - 182, http://dx.doi.org/10.1007/BF02215667
1996
Hunt SM; Tait AS; Gray PP; Sleigh MJ, 1996, 'Processing of mutated human proinsulin to mature insulin in the non-endocrine cell line, CHO', Cytotechnology, vol. 21, pp. 279 - 288, http://dx.doi.org/10.1007/BF00365350
1996
Pak SCO; Hunt SMN; Bridges MW; Sleigh MJ; Gray PP, 1996, 'Super-CHO - A cell line capable of autocrine growth under fully defined protein-free conditions', CYTOTECHNOLOGY, vol. 22, pp. 139 - 146, http://dx.doi.org/10.1007/BF00353933
1996
Cosgrove L; Lovrecz GO; Verkuylen A; Cavaleri L; Black LA; Bentley JD; Howlett GJ; Gray PP; Ward CS; Mckern N, 1995, 'Purification and properties of insulin receptor ectodomain from large-scale mammalian cell culture', Protein Expression and Purification, vol. 6, pp. 789 - 798, http://dx.doi.org/10.1006/prep.1995.0010
1995
Gebert CA; Gray PP, 1995, 'Expression of FSH in CHO celss II Stimulation of hFSH expression levels by defined medium supplements', Cytotechnology, vol. 17, pp. 13 - 19, http://dx.doi.org/10.1007/BF00749216
1995
Chotigeat W; Watanapokasin Y; Mahler S; Gray PP, 1994, 'Role of environmental conditions on the expression levels, glycoform pattern and levels of sialyltransferase for hFSH produced by recombinant CHO cells', Cytotechnology, vol. 15, pp. 217 - 221, http://dx.doi.org/10.1007/BF00762396
1994
Gebert CA; Gray PP, 1994, 'Expression of FSH in CHO cells I. Comparison of promoter types and effects of their respective inducers', Cytotechnology, vol. 14, pp. 39 - 45, http://dx.doi.org/10.1007/BF00772194
1994
Mitchell CA; Beall JA; Wells JRE; Gray PP, 1991, 'Growth and protein production kinetics of a murine myeloma cell line transfected with the human growth hormone gene', Cytotechnology, vol. 5, pp. 223 - 231, http://dx.doi.org/10.1007/BF00556292
1991
Gray PP; Marsden WL; Crowley J; Gebert C; Jirasripongpun K; Lovrecz G; Mitchell C; Mahler SM, 1990, 'Mammalian cell culture at the University of New South Wales.', Australian journal of biotechnology, vol. 4
1990
Friedman JS; Cofer CL; Anderson CL; Kushner JA; Gray PP; Chapman GE; Stuart MC; Lazarus L; Shine J; Kushner PJ, 1989, 'High expression in mammalian cells without amplification', Bio/Technology, vol. 7, pp. 359 - 362, http://dx.doi.org/10.1038/nbt0489-359
1989
McNeall J; Sánchez A; Gray PP; Chesterman CN; Sleigh MJ, 1989, 'Hyperinducible gene expression from a metallothionein promoter containing additional metal-responsive elements', Gene, vol. 76, pp. 81 - 88, http://dx.doi.org/10.1016/0378-1119(89)90010-3
1989
Fox DJ; Gray PP; Dunn NW; Marsden WL, 1989, 'Comparison of alkali and steam (acid) pretreatments of lignocellulosic materials to increase enzymic susceptibility: Evaluation under optimised pretreatment conditions', Journal of Chemical Technology & Biotechnology, vol. 44, pp. 135 - 146, http://dx.doi.org/10.1002/jctb.280440205
1989
Fox DJ; Gray PP; Dunn NW; Marsden WL, 1987, 'Factors affecting the enzymic susceptibility of alkali and acid pretreated sugar‐cane bagasse', Journal of Chemical Technology & Biotechnology, vol. 40, pp. 117 - 132, http://dx.doi.org/10.1002/jctb.280400204
1987
Gray PP; Vu‐Trong K, 1987, 'Production of the macrolide antibiotic tylosin in cyclic fed‐batch culture', Biotechnology and Bioengineering, vol. 29, pp. 33 - 40, http://dx.doi.org/10.1002/bit.260290106
1987
Vu-Trong K; Gray PP, 1987, 'Influence of ammonium on the biosynthesis of the macrolide antibiotic tylosin', Enzyme and Microbial Technology, vol. 9, pp. 590 - 593, http://dx.doi.org/10.1016/0141-0229(87)90110-4
1987
Gray PP; Vu-Trong K, 1987, 'Extended cyclic fed-batch tylosin fermentations', Biotechnology Letters, vol. 9, pp. 617 - 620, http://dx.doi.org/10.1007/BF01033197
1987
Morjanoff PJ; Gray PP, 1987, 'Optimization of steam explosion as a method for increasing susceptibility of sugarcane bagasse to enzymatic saccharification', Biotechnology and Bioengineering, vol. 29, pp. 733 - 741, http://dx.doi.org/10.1002/bit.260290610
1987
Vu-Trong K; Gray PP, 1986, 'Patterns of RNA synthesis in batch and cyclic fed-batch cultures of tylosin-producing Streptomyces fradiae', Biotechnology Letters, vol. 8, pp. 849 - 852, http://dx.doi.org/10.1007/BF01078643
1986
Marsden WL; Gray PP; Mandels M, 1985, 'Enzymatic hydrolysis of cellulose in lignocellulosic materials', Critical Reviews in Biotechnology, vol. 3, pp. 235 - 276, http://dx.doi.org/10.3109/07388558509150785
1985
FOX DJ; GRAY PP; DUNN NW; MARSDEN WL, 1984, 'AN EXPLANATION OF THE DISCREPANCY BETWEEN THE RESULTS OF HPLC AND DNS ASSAYS IN THE ANALYSIS OF LIGNOCELLULOSIC HYDROLYSATES', JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY B-BIOTECHNOLOGY, vol. 34, pp. 171 - 175, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1984TJ89000004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1984
Vu-Trong K; Gray PP, 1984, 'Stimulation of enzymes involved in tylosin biosynthesis by cyclic feeding profiles in fed batch cultures', Biotechnology Letters, vol. 6, pp. 435 - 440, http://dx.doi.org/10.1007/BF00129305
1984
Marsden WL; Dunn NW; Gray PP, 1983, 'Action of Trichoderma reesei QM9414 and C30 cellulase on substrates with varying crystallinity', Enzyme and Microbial Technology, vol. 5, pp. 345 - 351, http://dx.doi.org/10.1016/0141-0229(83)90006-6
1983
Fox D; Dunn NW; Gray PP; Marsden WL, 1983, 'SACCHARIFICATION OF BAGASSE USING A COUNTER-CURRENT PLUG-FLOW REACTOR.', Journal of chemical technology and biotechnology. Biotechnology, pp. 114 - 118, http://dx.doi.org/10.1002/jctb.280330206
1983
Allen GR; Reichelt JL; Gray PP, 1983, 'Influence of environmental factors and medium composition on Vibrio gazogenes growth and prodigiosin production', Applied and Environmental Microbiology, vol. 45, pp. 1727 - 1732, http://dx.doi.org/10.1128/aem.45.6.1727-1732.1983
1983
MARSDEN WL; GRAY PP; NIPPARD GJ; QUINLAN MR, 1982, 'EVALUATION OF THE DNS METHOD FOR ANALYZING LIGNOCELLULOSIC HYDROLYSATES', JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, vol. 32, pp. 1016 - 1022, http://dx.doi.org/10.1002/jctb.5030320744
1982
Marsden WL; Gray PP; Dunn NW, 1982, 'Alternative pathway for glucose production from cellulose using Trichoderma reesei QM9414 cellulase', Biotechnology Letters, vol. 4, pp. 589 - 594, http://dx.doi.org/10.1007/BF00127790
1982
Vu‐Trong K; Gray PP, 1982, 'Continuous‐culture studies on the regulation of tylosin biosynthesis', Biotechnology and Bioengineering, vol. 24, pp. 1093 - 1103, http://dx.doi.org/10.1002/bit.260240506
1982
Morjanoff P; Dunn NW; Gray PP, 1982, 'Improved enzymic digestibility of sugar cane bagasse following high temperature autohydrolysis', Biotechnology Letters, vol. 4, pp. 187 - 192, http://dx.doi.org/10.1007/BF00144322
1982
Vu-Trong K; Gray PP, 1982, 'Stimulation of tylosin productivity resulting from cyclic feeding profiles in fed batch cultures', Biotechnology Letters, vol. 4, pp. 725 - 728, http://dx.doi.org/10.1007/BF00134667
1982
Vu-Trong K; Bhuwapathanapun S; Gray PP, 1981, 'Metabolic regulation in tylosin-producing Streptomyces fradiae: phosphate control of tylosin biosynthesis', Antimicrobial Agents and Chemotherapy, vol. 19, pp. 209 - 212, http://dx.doi.org/10.1128/AAC.19.2.209
1981
Choudhury N; Dunn NW; Gray PP, 1981, 'Use of a combined Cellulomonas and Trichoderma cellulase preparation for cellulose saccharification', Biotechnology Letters, vol. 3, pp. 493 - 496, http://dx.doi.org/10.1007/BF00147560
1981
Gray PP; Bhuwapathanapun S, 1980, 'Production of the macrolide antibiotic tylosin in batch and chemostat cultures', Biotechnology and Bioengineering, vol. 22, pp. 1785 - 1804, http://dx.doi.org/10.1002/bit.260220903
1980
Vu-Trong K; Bhuwapathanapun S; Gray PP, 1980, 'Metabolic regulation in tylosin-producing Streptomyces fradiae: Regulatory role of adenylate nucleotide pool and enzymes involved in biosynthesis of tylonolide precursors', Antimicrobial Agents and Chemotherapy, vol. 17, pp. 519 - 525, http://dx.doi.org/10.1128/AAC.17.4.519
1980
Choudhury N; Gray PP; Dunn NW, 1980, 'Saccharification of sugar cane bagasse by an enzyme preparation from Cellulomonas: Resistance to product inhibition', Biotechnology Letters, vol. 2, pp. 427 - 428, http://dx.doi.org/10.1007/BF00162349
1980
Choudhury N; Gray PP; Dunn NW, 1980, 'Reducing sugar accumulation from alkali pretreated sugar cane bagasse using Cellulomonas', European Journal of Applied Microbiology and Biotechnology, vol. 11, pp. 50 - 54, http://dx.doi.org/10.1007/BF00514078
1980
Haggett KD; Gray PP; Dunn NW, 1979, 'Crystalline cellulose degradation by a strain of Cellulomonas and its mutant derivatives', European Journal of Applied Microbiology and Biotechnology, vol. 8, pp. 183 - 190, http://dx.doi.org/10.1007/BF00506182
1979
Hendy NA; Gray PP, 1979, 'Use of ATP as an indicator of biomass concentration in the Trichoderma viride fermentation', Biotechnology and Bioengineering, vol. 21, pp. 153 - 156, http://dx.doi.org/10.1002/bit.260210112
1979
Hewetson JW; Jong TH; Gray PP, 1979, 'Use of an immobilized penicillinase electrode in the monitoring of the penicillin fermentation', Biotechnology Bioengineering Symposium, vol. No. 9, pp. 125 - 135
1979
Whaite P; Gray PP, 1977, 'On‐line computer optimization chemostat productivity', Biotechnology and Bioengineering, vol. 19, pp. 575 - 581, http://dx.doi.org/10.1002/bit.260190413
1977
Gray PP; Rogers PL, 1971, 'I. Cytochrome oscillations in continuous culture. Action of chloramphenicol on Saccharomyces carlsbergensis and Candida utilis', BBA - General Subjects, vol. 230, pp. 393 - 400, http://dx.doi.org/10.1016/0304-4165(71)90226-1
1971
Gray PP; Rogers PL, 1971, 'II. Mathematical simulation of ctytochrome oscillations', BBA - General Subjects, vol. 230, pp. 401 - 410, http://dx.doi.org/10.1016/0304-4165(71)90227-3
1971
Gray PP; Rogers PL, 1971, 'Action of chloramphenicol and cycloheximide on saccharomyces carlsbergensis: Batch and continuous studies', Australian Journal of Biological Sciences, vol. 24, pp. 487 - 496, http://dx.doi.org/10.1071/BI9710487
1971
Conference Papers
add
Pak SC; Hunt SM; Bridges MW; Sleigh MJ; Gray PP, 1996, 'Super-CHO-a cell line capable of autocrine growth under fully defined protein free conditions', in Cytotechnology, Kluwer Academic Publ, Dordrecht, Netherlands, pp. 139 - 146, presented at Cell Culture Engineering, http://dx.doi.org/10.1007/BF00353933
1996