When chemical reactions in the human body are disrupted, it can result in many different types of metabolic disorders; each with varying symptoms that can include high blood pressure, high sugar level and excessive body fat.

Supported by researchers and investigators, UNSW aims to address these syndromes and develop new treatments and strategies. Our researchers are currently looking to combat metabolic diseases such as cardiovascular disease, obesity, type 2 diabetes and cancer. We examine lipid metabolism and glucose metabolism to better understand how cells use nutrients such as fat, amino acids, cholesterols and sugars.

Students employ molecular cell biological technologies, pre-clinical models and state-of-the-art microscopy to look at metabolic pathways and inborn errors of metabolism. Our students develop their skills in data interpretation and report writing, along with using analytical techniques such as mass spectrometry.

UNSW research in metabolism and metabolic disorders has undergone considerable growth in scope and output, producing high impact publications and secured national competitive grants. Notably, UNSW School of Biotechnology and Biomolecular Sciences Professor Rob Yang carried out extensive research into metabolic disorders with a breakthrough discovery in the transportation of cholesterol in cells. This new knowledge can be applied to developing drugs that will boost good cholesterol and alleviate the risk of heart disease and stroke in the years to come. 

Professor H Robert Yang and Dr Ivan Lukmantara
Professor H Robert Yang and Dr Ivan Lukmantara