Recombinant reductive dehalogenases

Reductive dehalogenases are enzymes involved in the reductive dechlorination of polychlorinated hydrocarbons, such as hexachlorobenzene. Microbial processes to degrade hexachlorobenzene and other chlorinated hydrocarbons have been described, however the anaerobic processes in particular are relatively slow, because of low cell densities, slow growth rates and low substrate concentrations.

This project will aim to identify a candidate reductive dehalogenase, followed by generating and evaluating a recombinant version of the enzyme.

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